Gene Symbol | Scd2 |
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Entrez Gene | 20250 |
Alt Symbol | Mir5114, Scd-2, mir-5114, swty |
Species | Mouse |
Gene Type | protein-coding |
Description | stearoyl-Coenzyme A desaturase 2 |
Other Description | Acyl-CoA desaturase 2 (Stearoyl-CoA desaturase 2) (Fatty acid desaturase 2) (Delta(9)-desaturase 2)|acyl-CoA desaturase 2|delta(9)-desaturase 2|delta-9 desaturase 2|fatty acid desaturase 2|stearoyl-CoA desaturase 2 |
Swissprots | P13011 Q8BH96 |
Accessions | EDL41928 P13011 AK078543 AK083085 AK083922 BAC39066 AK147406 BAE27893 AK159413 BC040384 AAH40384 CF168778 CJ110442 CJ242760 JF446414 LM611522 M26270 AAA40094 NM_009128 NP_033154 |
Function | Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Top Pathways | PPAR signaling pathway, AMPK signaling pathway, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism |
SCD2 CRISPR/Cas9 KO Plasmid (m) - sc-422810 from Santa Cruz Biotechnology
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SCD2 HDR Plasmid (m) - sc-422810-HDR from Santa Cruz Biotechnology
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SCD2 Double Nickase Plasmid (m) - sc-422810-NIC from Santa Cruz Biotechnology
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SCD2 Double Nickase Plasmid (m2) - sc-422810-NIC-2 from Santa Cruz Biotechnology
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SCD2 CRISPR Activation Plasmid (m) - sc-422810-ACT from Santa Cruz Biotechnology
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SCD2 CRISPR Activation Plasmid (m2) - sc-422810-ACT-2 from Santa Cruz Biotechnology
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SCD2 Lentiviral Activation Particles (m) - sc-422810-LAC from Santa Cruz Biotechnology
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SCD2 Lentiviral Activation Particles (m2) - sc-422810-LAC-2 from Santa Cruz Biotechnology
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SCD2 siRNA (m) - sc-41654 from Santa Cruz Biotechnology
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SCD2 shRNA Plasmid (m) - sc-41654-SH from Santa Cruz Biotechnology
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SCD2 shRNA (m) Lentiviral Particles - sc-41654-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU092091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN40754 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40754 from Sigma-Aldrich
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SCD2 siRNA (Mouse) - CRM3602 from Cohesion Biosciences
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SCD2 - MBS8203253 from MyBioSource
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Mouse SCD2 siRNA - orb283078 from Biorbyt
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SCD2 shRNA Plasmid (Mouse) - CHM3602 from Cohesion Biosciences
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