Gene Symbol |
Scd2
|
Entrez Gene |
20250
|
Alt Symbol |
Mir5114, Scd-2, mir-5114, swty
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
stearoyl-Coenzyme A desaturase 2
|
Other Description |
Acyl-CoA desaturase 2 (Stearoyl-CoA desaturase 2) (Fatty acid desaturase 2) (Delta(9)-desaturase 2)|acyl-CoA desaturase 2|delta(9)-desaturase 2|delta-9 desaturase 2|fatty acid desaturase 2|stearoyl-CoA desaturase 2
|
Swissprots |
P13011 Q8BH96
|
Accessions |
EDL41928 P13011 AK078543 AK083085 AK083922 BAC39066 AK147406 BAE27893 AK159413 BC040384 AAH40384 CF168778 CJ110442 CJ242760 JF446414 LM611522 M26270 AAA40094 NM_009128 NP_033154
|
Function |
Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
Top Pathways |
PPAR signaling pathway, AMPK signaling pathway, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism
|