TRPC4

Gene Symbol TRPC4
Entrez Gene 7223
Alt Symbol HTRP-4, HTRP4, TRP4
Species Human
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily C, member 4
Other Description short transient receptor potential channel 4|trp-related protein 4
Swissprots Q9UIB2 Q9UBN4 B1ALE1 B1ALE0 Q9UIB1 Q96P03 B1ALE2 Q9UIB0 Q15721 Q96P04 Q96P05 Q3SWS6
Accessions EAX08595 EAX08596 EAX08597 EAX08598 EAX08599 EAX08600 EAX08601 Q9UBN4 AF063822 AAF22927 AF063823 AAF22928 AF063824 AAF22929 AF063825 AAF22930 AF175406 AAD51736 AF421358 AAL24549 AF421359 AAL24550 AF421360 AAL24551 AF421361 AAL24552 AF421362 AAL24553 AK312524 BAG35423 BC104725 AAI04726 BC105306 AAI05307 BC105641 AAI05642 BC105917 AAI05918 BX648312 CN364204 DB258184 DB278337 DB308366 U40983 AAC50630 XM_011535206 XP_011533508 XM_011535207 XP_011533509 NM_001135955 NP_001129427 NM_001135956 NP_001129428 NM_001135957 NP_001129429 NM_001135958 NP_001129430 NM_003306 NP_003297 NM_016179 NP_057263
Function Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion. {ECO:0000269|PubMed:16144838, ECO:0000269|PubMed:19996314}.
Subcellular Location Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Enhanced insertion into the cell membrane after activation of the EGF receptor.
Tissue Specificity Strongly expressed in placenta. Expressed at lower levels in heart, pancreas, kidney and brain. Expressed in endothelial cells. Isoform alpha was found to be the predominant isoform. Isoform beta was not found in pancreas and brain. {ECO:0000269|PubMed:19996314}.

TRPC4 (C-20) - sc-15063 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRPC4 (A-18) - sc-15061 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRPC4 (A-18): sc-15061. Western blot analysis of TRPC4 expression in mouse heart tissue extract.

TRPC4/5 (H-80) - sc-28760 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRPC4/5 (H-80): sc-28760. Immunofluorescence staining of normal mouse heart frozen section showing membrane staining.

Anti-TRPC4 antibody - ab63128 from Abcam

Host Sheep
Clonality Polyclonal

Anti-TRPC4 Antibody (aa943-958) - LS-C76592 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC4 Antibody (4th Cytoplasmic Domain) - LS-C94463 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-TRPC4 Antibody (1st Cytoplasmic Domain) - LS-C136494 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRPC4 Antibody - LS-C132695 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TRPC4 Antibody (clone S77-15) - LS-C152679 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 390) - LS-C227634 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 594) - LS-C227636 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 488) - LS-C227635 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 565) - LS-C227637 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 633) - LS-C227638 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 655) - LS-C227639 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 680) - LS-C227640 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Atto 700) - LS-C227641 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, AP) - LS-C227642 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, APC) - LS-C227643 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, FITC) - LS-C227645 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, Biotin) - LS-C227644 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, PE, Atto 594) - LS-C227647 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, PerCP) - LS-C227648 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, RPE) - LS-C227649 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15

Anti-TRPC4 Antibody (aa930-947, clone S77-15, SA) - LS-C227650 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S77-15
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