| Gene Symbol |
GAREM
|
| Entrez Gene |
64762
|
| Alt Symbol |
C18orf11, FAM59A, Gm944
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GRB2 associated, regulator of MAPK1
|
| Other Description |
GRB2-associated and regulator of MAPK protein|GRB2-associated and regulator of MAPK1|Grb2-associated and regulator of Erk/MAPK|family with sequence similarity 59, member A|protein FAM59A
|
| Swissprots |
Q8ND03 Q9H706 Q0VAG3 Q0VAG4 Q9BSF5
|
| Accessions |
EAX01286 EAX01287 Q9H706 AF086529 AI479499 AK025263 BAB15094 AK025660 AK297430 BAG59858 AL834491 CAD39149 BC005074 AAH05074 BC121067 AAI21068 BC121068 AAI21069 XM_011526139 XP_011524441 XM_011526140 XP_011524442 NM_001242409 NP_001229338 NM_022751 NP_073588
|
| Function |
Isoform 1: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation. {ECO:0000269|PubMed:19509291}.
|
| Tissue Specificity |
Isoform 1 is ubiquitously expressed. {ECO:0000269|PubMed:19509291}.
|