Gene Symbol | Hr |
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Entrez Gene | 15460 |
Alt Symbol | ALUNC, AU, N, ba, bldy, hr, rh, rh-bmh, rhino |
Species | Mouse |
Gene Type | protein-coding |
Description | hairless |
Other Description | lysine-specific demethylase hairless|protein hairless |
Swissprots | Q80Y47 Q61645 |
Accessions | EDL35888 EDL35889 EDL35890 Q61645 AB221596 AB221597 AK076280 AY312855 AY547390 AY547391 AAT45233 BC023043 BC023157 BC025463 BC048552 BC049182 AAH49182 Z32675 CAA83587 XM_011244966 XP_011243268 NM_021877 NP_068677 |
Function | Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed predominantly in brain, hair follicles and interfollicular epidermis. No expression in dermis. |
HR CRISPR/Cas9 KO Plasmid (m) - sc-420945 from Santa Cruz Biotechnology
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HR HDR Plasmid (m) - sc-420945-HDR from Santa Cruz Biotechnology
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HR Double Nickase Plasmid (m) - sc-420945-NIC from Santa Cruz Biotechnology
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HR Double Nickase Plasmid (m2) - sc-420945-NIC-2 from Santa Cruz Biotechnology
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HR CRISPR Activation Plasmid (m) - sc-420945-ACT from Santa Cruz Biotechnology
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HR CRISPR Activation Plasmid (m2) - sc-420945-ACT-2 from Santa Cruz Biotechnology
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HR Lentiviral Activation Particles (m) - sc-420945-LAC from Santa Cruz Biotechnology
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HR Lentiviral Activation Particles (m2) - sc-420945-LAC-2 from Santa Cruz Biotechnology
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HR siRNA (m) - sc-146075 from Santa Cruz Biotechnology
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HR shRNA Plasmid (m) - sc-146075-SH from Santa Cruz Biotechnology
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HR shRNA (m) Lentiviral Particles - sc-146075-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU010961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33454 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33454 from Sigma-Aldrich
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HR siRNA (Mouse) - CRM1916 from Cohesion Biosciences
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HR - MBS8238907 from MyBioSource
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HR CRISPR/Cas9 KO Plasmid (m2) - sc-420945-KO-2 from Santa Cruz Biotechnology
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HR HDR Plasmid (m2) - sc-420945-HDR-2 from Santa Cruz Biotechnology
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Mouse HR siRNA - orb281392 from Biorbyt
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HR shRNA Plasmid (Mouse) - CHM1916 from Cohesion Biosciences
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HR miRNA 3'UTR clone - MiUTR1M-05779 from Creative biogene
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