Gene Symbol |
Hr
|
Entrez Gene |
15460
|
Alt Symbol |
ALUNC, AU, N, ba, bldy, hr, rh, rh-bmh, rhino
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
hairless
|
Other Description |
lysine-specific demethylase hairless|protein hairless
|
Swissprots |
Q80Y47 Q61645
|
Accessions |
EDL35888 EDL35889 EDL35890 Q61645 AB221596 AB221597 AK076280 AY312855 AY547390 AY547391 AAT45233 BC023043 BC023157 BC025463 BC048552 BC049182 AAH49182 Z32675 CAA83587 XM_011244966 XP_011243268 NM_021877 NP_068677
|
Function |
Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus.
|
Tissue Specificity |
Expressed predominantly in brain, hair follicles and interfollicular epidermis. No expression in dermis.
|