Gene Symbol | INHBB |
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Entrez Gene | 3625 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | inhibin, beta B |
Other Description | Inhibin, beta-2|activin AB beta polypeptide|activin beta-B chain|inhibin beta B chain |
Swissprots | Q53T31 P09529 Q8N1D3 |
Accessions | AAA59451 AAY14801 EAW95243 P09529 AA416873 AI659282 BC030029 AAH30029 BC127815 AAI27816 BF938974 CK430845 DQ890708 ABM81634 M13437 AAA59169 M31682 AAA59170 NM_002193 NP_002184 |
Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Inhibin β-B CRISPR/Cas9 KO Plasmid (h) - sc-402060 from Santa Cruz Biotechnology
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Inhibin β-B HDR Plasmid (h) - sc-402060-HDR from Santa Cruz Biotechnology
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Inhibin β-B Double Nickase Plasmid (h) - sc-402060-NIC from Santa Cruz Biotechnology
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Inhibin β-B Double Nickase Plasmid (h2) - sc-402060-NIC-2 from Santa Cruz Biotechnology
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Inhibin β-B CRISPR Activation Plasmid (h) - sc-402060-ACT from Santa Cruz Biotechnology
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Inhibin β-B CRISPR Activation Plasmid (h2) - sc-402060-ACT-2 from Santa Cruz Biotechnology
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Inhibin β-B Lentiviral Activation Particles (h) - sc-402060-LAC from Santa Cruz Biotechnology
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Inhibin β-B Lentiviral Activation Particles (h2) - sc-402060-LAC-2 from Santa Cruz Biotechnology
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Inhibin β-B siRNA (h) - sc-43861 from Santa Cruz Biotechnology
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Inhibin β-B shRNA Plasmid (h) - sc-43861-SH from Santa Cruz Biotechnology
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Inhibin β-B shRNA (h) Lentiviral Particles - sc-43861-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10678 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10678 from Sigma-Aldrich
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INHBB siRNA (Human) - CRH2429 from Cohesion Biosciences
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Inhibin beta B RNAi - H00003625-R01 from Novus Biologicals
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INHBB - MBS8231119 from MyBioSource
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shRNA set against Human INHBB (NM_002193.2) - SHH319553 from Creative biogene
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shRNA set against Human INHBB(NM_002193.2) - SHL178108 from Creative biogene
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INHBB shRNA Plasmid (Human) - CHH2429 from Cohesion Biosciences
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INHBB miRNA 3'UTR clone - MiUTR3H-01200 from Creative biogene
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