Gene Symbol | INHBB |
---|---|
Entrez Gene | 3625 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | inhibin, beta B |
Other Description | Inhibin, beta-2|activin AB beta polypeptide|activin beta-B chain|inhibin beta B chain |
Swissprots | Q53T31 P09529 Q8N1D3 |
Accessions | AAA59451 AAY14801 EAW95243 P09529 AA416873 AI659282 BC030029 AAH30029 BC127815 AAI27816 BF938974 CK430845 DQ890708 ABM81634 M13437 AAA59169 M31682 AAA59170 NM_002193 NP_002184 |
Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |