Gene Symbol |
SYT2
|
Entrez Gene |
127833
|
Alt Symbol |
MYSPC, SytII
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
synaptotagmin II
|
Other Description |
synaptotagmin-2
|
Swissprots |
Q8NBE5 Q496K5 Q8N9I0
|
Accessions |
EAW91429 EAW91430 Q8N9I0 AK090672 BAC03500 AK094430 BAC04354 AK124510 BC100814 AAI00815 BC100815 AAI00816 BC100816 AAI00817 BC100817 AAI00818 DA098279 XM_011509191 XP_011507493 XM_011509192 XP_011507494 NM_001136504 NP_001129976 NM_177402 NP_796376
|
Function |
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Synaptic vesicles and chromaffin granules. {ECO:0000250}.
|