Gene Symbol | MARCH9 |
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Entrez Gene | 92979 |
Alt Symbol | MARCH-IX, RNF179 |
Species | Human |
Gene Type | protein-coding |
Description | membrane-associated ring finger (C3HC4) 9 |
Other Description | E3 ubiquitin-protein ligase MARCH9|RING finger protein 179|membrane-associated RING finger protein 9|membrane-associated RING-CH protein IX |
Swissprots | Q86YJ5 B2R9U9 Q86VN5 Q96GG2 |
Accessions | EAW97063 EAW97064 EAW97065 Q86YJ5 AK093897 BAC04247 AK313925 BAG36646 BC009489 AAH09489 BC036455 AAH36455 BC050397 AAH50397 XM_011539007 XP_011537309 NM_138396 NP_612405 |
Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000269|PubMed:14722266, ECO:0000269|PubMed:17174307}. |
Subcellular Location | Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:14722266}. |
Human MARCH9 full length protein - ab164928 from Abcam
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Human MARCH9 protein fragment - ab164929 from Abcam
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MARCH9 Antibody Blocking Peptide - LS-E4973 from LifeSpan Bioscience
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MARCH9 Antibody Blocking Peptide - LS-E15964 from LifeSpan Bioscience
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Recombinant Human MARCH9 Protein - H00092979-P01 from Novus Biologicals
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Recombinant Human MARCH9 Protein - H00092979-Q01 from Novus Biologicals
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MARCH9-Antibody-C-term-Blocking-Peptide - BP17367b from Abgent, a WuXi AppTec company
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RNF179 Blocking Peptide - 33R-8781 from Fitzgerald
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MARCH9 / RNF179 - H00092979-P01-10 from Acris Antibodies
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MARCH9 / RNF179 - H00092979-P01-25 from Acris Antibodies
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MARCH9 / RNF179 - H00092979-Q01-10 from Acris Antibodies
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MARCH9 / RNF179 - H00092979-Q01-25 from Acris Antibodies
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Recombinant Brain Finger Protein (BFP) - RPB093Hu01 from Cloud-clone
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E3 ubiquitin-protein ligase MARCH9 (MARCH9), Recombinant Protein - MBS7006889 from MyBioSource
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MARCH9 fusion protein - Ag26607 from Proteintech Group
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