TNNC1

Gene Symbol TNNC1
Entrez Gene 7134
Alt Symbol CMD1Z, CMH13, TN-C, TNC, TNNC
Species Human
Gene Type protein-coding
Description troponin C type 1 (slow)
Other Description cardiac troponin C|slow twitch skeletal/cardiac muscle troponin C|troponin C, slow skeletal and cardiac muscles|troponin C1, slow
Swissprots P63316
Accessions AAA36772 ADL14491 EAW65226 EAW65227 P63316 AF020769 AAB91994 AJ574625 AK313743 BAG36483 BC030244 AAH30244 CR541865 CAG46663 CR541885 CAG46683 DQ891026 ABM81952 DQ894206 ABM85132 X07897 CAA30736 NM_003280 NP_003271
Function Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Top Pathways Calcium signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

Troponin C slow skeletal/cardiac (12G3) - sc-52263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin C slow skeletal/cardiac (12G3): sc-52263. Western blot analysis of Troponin C slow skeletal/cardiac expression in SJRH30 (A), HISM (B) and HeLa (C) whole cell lysates.

Troponin C slow skeletal/cardiac (1A2) - sc-52264 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin C slow skeletal/cardiac (1A2): sc-52264. Western blot analysis of Troponin C slow skeletal/cardiac expression in SJRH30 (A), HISM (B) and HeLa (C) whole cell lysates.

Troponin C slow skeletal/cardiac (7B9) - sc-52265 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin C slow skeletal/cardiac (7B9): sc-52265. Western blot analysis of Troponin C slow skeletal/cardiac expression in SJRH30 whole cell lysate.

Troponin C slow skeletal/cardiac (N-15) - sc-49555 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cardiac Troponin C antibody [12G3] - ab10245 from Abcam

Prices $378.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 12G3
ab10245 staining Cardiac Troponin C in Human sternal bone marrow derived MSCs induced to cardio by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with Triton X-100 and blocked with 10% serum for 1 hour at 37°C. Samples were incubated with primary antibody (1/250 in PBS + 1% Goat serum) for 18 hours at 4°C. An Alexa Fluor® 488-conjugated Goat anti-mouse IgG polyclonal (1/300) was used as the secondary antibody.See Abreview

Anti-Cardiac Troponin C antibody [1A2] - ab8285 from Abcam

Prices $379.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1A2
Ab8285 staining Human normal skeletal muscle. Staining is localised to the cytoplasm.Left panel: with primary antibody at 1 ug/ml. Right panel: isotype control.Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 AR buffer citrate pH6.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 minutes. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS), then incubated with primary antibody for 20 minutes, and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-Cardiac Troponin C antibody [3A10A12] - ab31980 from Abcam

Host Mouse
Clonality Monoclonal
Clone 3A10A12
All lanes : Anti-Cardiac Troponin C antibody [3A10A12] (ab31980)Lane 1 : Molecular weight markerLane 2 : Truncated recombinant human cardiac troponin C protein

Anti-Cardiac Troponin C antibody [7B9] - ab38174 from Abcam

Prices $370.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 7B9

Anti-Cardiac Troponin C antibody [7B9] (HRP) - ab8286 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 7B9

Anti-Cardiac Troponin C antibody [8.F.287] - ab30806 from Abcam

Prices $370.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 8.F.287

Anti-Cardiac Troponin C antibody [EPR9692(B)] - ab137130 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9692(B)
All lanes : Anti-Cardiac Troponin C antibody [EPR9692(B)] (ab137130) at 1/1000 dilutionLane 1 : Fetal heart lysateLane 2 : Human skeletal muscle lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Cardiac troponin complex antibody [20C6] - ab82620 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 20C6

Anti-TNNC1 antibody - ab180732 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab180732. Blue DAPI for nuclear staining.

Anti-TNNC1 antibody - ab196683 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TNNC1 antibody (ab196683) at 1/500 dilutionLane 1 : Mouse heart cell extractsLane 2 : Mouse lung cell extractsLane 3 : Mouse skeletal muscle cell extracts

Anti-TNNC1 antibody - ab192376 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNNC1 antibody - N-terminal - ab191444 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TNNC1 antibody - N-terminal (ab191444) at 0.5 µg/ml + Rat skeletal muscle tissue lysate

Anti-TNNC1 / Cardiac Troponin C Antibody (aa1-18) - LS-C312925 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
TNNC1 / Cardiac Troponin C antibody. IHC(P): Rat Cardiac Muscle Tissue.

Anti-TNNC1 / Cardiac Troponin C Antibody (clone 1F8-A9) IHC-plus™ - LS-B6157 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1F8-A9
Anti-TNNC1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6157 concentration 5 ug/ml.

Anti-TNNC1 / Cardiac Troponin C Antibody - LS-C39867 from LifeSpan Bioscience

Prices $530.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal

Anti-TNNC1 / Cardiac Troponin C Antibody - LS-C39869 from LifeSpan Bioscience

Prices $530.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal

Anti-TNNC1 / Cardiac Troponin C Antibody - LS-C39868 from LifeSpan Bioscience

Prices $530.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal

Anti-TNNC1 / Cardiac Troponin C Antibody (clone 12G3) - LS-C52523 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 12G3

Anti-TNNC1 / Cardiac Troponin C Antibody (clone 7B9) - LS-C52525 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 7B9

Anti-TNNC1 / Cardiac Troponin C Antibody (clone 1A2) - LS-C52524 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1A2

Anti-TNNC1 / Cardiac Troponin C Antibody (clone 7B9) - LS-C85471 from LifeSpan Bioscience

Prices $650.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal
Clone 7B9
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