PPAP2B

Gene Symbol	PPAP2B
Entrez Gene	8613
Alt Symbol	Dri42, LPP3, PAP2B, VCIP
Species	Human
Gene Type	protein-coding
Description	phosphatidic acid phosphatase type 2B
Other Description	PAP2 beta|lipid phosphate phosphohydrolase 3|phosphatidate phosphohydrolase type 2b|type-2 phosphatidic acid phosphatase-beta|vascular endothelial growth factor and type I collagen inducible
Swissprots	Q99782 Q96GW0 O14495 Q5U0F7 D3DQ52 B2R651
Accessions	EAX06651 EAX06652 EAX06653 O14495 AB000889 BAA22594 AF017786 AAC63433 AF043329 AAD02271 AF480883 AAO84481 AK123105 AK312439 BAG35348 BC009196 AAH09196 BM471786 BM719257 BQ027458 BT019589 AAV38396 BU608248 BU616092 DA580891 DQ893521 ABM84447 DQ895944 ABM86870 U79294 AAB50222 NM_003713 NP_003704 NM_177414
Function	Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions.
Subcellular Location	Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Ubiquitously expressed. Highly expressed in heart and placenta.
Top Pathways	Fc gamma R-mediated phagocytosis, Fat digestion and absorption, Choline metabolism in cancer, Ether lipid metabolism, Glycerolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAP-2b CRISPR/Cas9 KO Plasmid (h) - sc-411194 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b HDR Plasmid (h) - sc-411194-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b Double Nickase Plasmid (h) - sc-411194-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b Double Nickase Plasmid (h2) - sc-411194-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b CRISPR Activation Plasmid (h) - sc-411194-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b CRISPR Activation Plasmid (h2) - sc-411194-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b Lentiviral Activation Particles (h) - sc-411194-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b Lentiviral Activation Particles (h2) - sc-411194-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAP-2b siRNA (h) - sc-106783 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PAP-2b shRNA Plasmid (h) - sc-106783-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PAP-2b shRNA (h) Lentiviral Particles - sc-106783-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PPAP2B RNAi - H00008613-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PPAP2B RNAi - H00008613-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU056771 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0440 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0994 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0995 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0441 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0439 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17197 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17197 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10392 from Sigma-Aldrich Category miRNA

PPAP2B siRNA (Human) - CRH5659 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PPAP2B (NM_003713.4) - SHH380252 from Creative biogene Category siRNA Species Reactivities Human

Human PPAP2B siRNA - orb266161 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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