Gene Symbol | KRTAP8-1 |
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Entrez Gene | 337879 |
Alt Symbol | KAP8.1 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 8-1 |
Other Description | high glycine-tyrosine keratin-associated protein 8.1|keratin-associated protein 8-1 |
Swissprots | Q8IUC2 Q3LI57 |
Accessions | EAX09896 Q8IUC2 AB096961 BAE46376 AJ457064 CAD29720 BC130397 AAI30398 BC133033 AAI33034 NM_175857 NP_787053 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Is essentially restricted to only one vertical half of the hair forming compartment and in beard hairs is absent from the central medulla. |
KRTAP8-1 CRISPR/Cas9 KO Plasmid (h) - sc-415477 from Santa Cruz Biotechnology
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KRTAP8-1 HDR Plasmid (h) - sc-415477-HDR from Santa Cruz Biotechnology
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KRTAP8-1 Double Nickase Plasmid (h) - sc-415477-NIC from Santa Cruz Biotechnology
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KRTAP8-1 Double Nickase Plasmid (h2) - sc-415477-NIC-2 from Santa Cruz Biotechnology
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KRTAP8-1 CRISPR Activation Plasmid (h) - sc-415477-ACT from Santa Cruz Biotechnology
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KRTAP8-1 CRISPR Activation Plasmid (h2) - sc-415477-ACT-2 from Santa Cruz Biotechnology
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KRTAP8-1 Lentiviral Activation Particles (h) - sc-415477-LAC from Santa Cruz Biotechnology
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KRTAP8-1 Lentiviral Activation Particles (h2) - sc-415477-LAC-2 from Santa Cruz Biotechnology
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KRTAP8-1 siRNA (h) - sc-91373 from Santa Cruz Biotechnology
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KRTAP8-1 shRNA Plasmid (h) - sc-91373-SH from Santa Cruz Biotechnology
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KRTAP8-1 shRNA (h) Lentiviral Particles - sc-91373-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11494 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11494 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12030 from Sigma-Aldrich
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KRTAP8-1 siRNA (Human) - CRJ7209 from Cohesion Biosciences
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shRNA set against Human KRTAP8-1(NM_175857.3) - SHH139961 from Creative biogene
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Human KRTAP8-1 siRNA - orb277710 from Biorbyt
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KRTAP8-1 shRNA Plasmid (Human) - CHJ7209 from Cohesion Biosciences
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KRTAP8-1 miRNA 3'UTR clone - MiUTR1H-05533 from Creative biogene
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