CA2

Gene Symbol	CA2
Entrez Gene	760
Alt Symbol	CA-II, CAC, CAII, Car2, HEL-76
Species	Human
Gene Type	protein-coding
Description	carbonic anhydrase II
Other Description	carbonate dehydratase II|carbonic anhydrase 2|carbonic anhydrase B|carbonic anhydrase C|carbonic dehydratase|epididymis luminal protein 76
Swissprots	Q96ET9 P00918 Q6FI12 B2R7G8
Accessions	AAA51909 CAA27012 EAW87136 P00918 AF015039 AK123309 AK312978 BAG35815 BC011949 AAH11949 BC035424 CD013933 CR536526 CAG38763 CR541875 CAG46673 DA431650 DQ891320 ABM82246 DQ894504 ABM85430 FJ224289 ACI45981 J03037 AAA51908 M36532 AAA51911 S69526 AAB30170 Y00339 CAA68426 NM_000067 NP_000058 NM_001293675 NP_001280604
Function	Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000250, ECO:0000269|PubMed:10550681, ECO:0000269|PubMed:11831900, ECO:0000269|PubMed:15990874}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15990874}. Cell membrane {ECO:0000269|PubMed:15990874}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Top Pathways	Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CA2 gene - orb91058 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-CA2-cDNA-Clone - DC03246 from Abgent, a WuXi AppTec company Prices $351.00 Sizes 10 µg Species Human Accession BC011949

CA2 - MBS1275074 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC011949

Human CA2 ORF Clone(NM_000067.2) - CDCL157190 from Creative Biomart Species Human Accession NM_000067.2

Human Carbonic Anhydrase II Gene ORF cDNA clone in cloning vector - HG10478-M from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10478-NF from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10478-NM from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, C-HA tag - HG10478-CY from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10478-CF from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, N-HA tag - HG10478-NY from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10478-CM from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, C-His tag - HG10478-CH from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10478-ANG from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10478-ACR from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10478-ANR from Sino Biological Species Human

Human CA II Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10478-M-N from Sino Biological Species Human Accession NM_000067.2

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid - HG10478-UT from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, N-His tag - HG10478-NH from Sino Biological Species Human

Human Carbonic Anhydrase II Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10478-ACG from Sino Biological Species Human

Human CA II Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10478-M-F from Sino Biological Species Human Accession NM_000067.2

CA2 - CL01290H01 from Elabscience Species Human Accession NM_000067.2

Human CA II ORF clone(NM_000067.2) - CDCL182992 from Creative biogene Species Human

Human CA2 ORF Clone (BC011949) - CDCS405392 from Creative biogene Species Human Accession P00918

Human SLC25A20 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG16996-ACG from Sino Biological Species Human

Human SLC25A20 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG16996-ACR from Sino Biological Species Human

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