Gene Symbol | PLCB3 |
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Entrez Gene | 5331 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase C, beta 3 (phosphatidylinositol-specific) |
Other Description | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3|PLC beta 3|PLC-beta-3|phosphoinositide phospholipase C-beta-3 |
Swissprots | G5E960 A5PKZ6 Q8N1A4 Q01970 |
Accessions | AAA77683 CAA85776 CBF62886 CBF74559 CBU87762 CBU96709 EAW74230 EAW74231 Q01970 AB385031 BAG10887 BC032659 AAH32659 BC041625 BC142681 AAI42682 BC146645 Z16411 CAA78903 Z26649 XM_005274052 XP_005274109 XM_011545101 XP_011543403 NM_000932 NP_000923 NM_001184883 NP_001171812 |
Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. |
Subcellular Location | Membrane; Peripheral membrane protein. |
Top Pathways | Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels |
PLC β3 siRNA (h) - sc-36272 from Santa Cruz Biotechnology
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PLC β3 shRNA Plasmid (h) - sc-36272-SH from Santa Cruz Biotechnology
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PLC β3 shRNA (h) Lentiviral Particles - sc-36272-V from Santa Cruz Biotechnology
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PLC β3 siRNA (h2) - sc-44321 from Santa Cruz Biotechnology
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PLC β3 shRNA Plasmid (h2) - sc-44321-SH from Santa Cruz Biotechnology
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PLC β3 shRNA (h2) Lentiviral Particles - sc-44321-V from Santa Cruz Biotechnology
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PLC-beta 3 RNAi - H00005331-R01 from Novus Biologicals
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MISSION® esiRNA - EHU145831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16922 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16922 from Sigma-Aldrich
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PLCB3 siRNA (Human) - CRH3571 from Cohesion Biosciences
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shRNA set against Human Plcb3 (NM_000932.2) - SHH377132 from Creative biogene
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PLCB3 shRNA Plasmid (Human) - CHH3571 from Cohesion Biosciences
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