| Gene Symbol | PLCB3 |
|---|---|
| Entrez Gene | 5331 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| Other Description | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3|PLC beta 3|PLC-beta-3|phosphoinositide phospholipase C-beta-3 |
| Swissprots | G5E960 A5PKZ6 Q8N1A4 Q01970 |
| Accessions | AAA77683 CAA85776 CBF62886 CBF74559 CBU87762 CBU96709 EAW74230 EAW74231 Q01970 AB385031 BAG10887 BC032659 AAH32659 BC041625 BC142681 AAI42682 BC146645 Z16411 CAA78903 Z26649 XM_005274052 XP_005274109 XM_011545101 XP_011543403 NM_000932 NP_000923 NM_001184883 NP_001171812 |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. |
| Subcellular Location | Membrane; Peripheral membrane protein. |
| Top Pathways | Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels |