ACSL6

Gene Symbol ACSL6
Entrez Gene 23305
Alt Symbol ACS2, FACL6, LACS 6, LACS2, LACS5
Species Human
Gene Type protein-coding
Description acyl-CoA synthetase long-chain family member 6
Other Description fatty-acid-Coenzyme A ligase, long-chain 6|long fatty acyl-CoA synthetase 2|long-chain-fatty-acid--CoA ligase 6
Swissprots Q9UKU0 J3KPG3 O94924 Q86TN7 Q108N0 O95829 Q4G191 Q108M9
Accessions EAW62355 EAW62356 EAW62357 EAW62358 EAW62359 EAW62360 Q9UKU0 AB020644 BAA74860 AF102845 AF129166 AAD47199 AK122702 BAG53676 AK294291 BAG57574 AK314452 BAG37060 AW952652 BC026161 AAH26161 BC047453 AAH47453 BI464352 BI545119 BI548729 BM992189 DA200154 DA801862 DB461818 DQ083030 AAZ30713 DQ083031 AAZ30714 DQ655980 JF432422 ADZ15639 NM_001009185 NP_001009185 NM_001205247 NP_001192176 NM_001205248 NP_001192177 NM_001205250 NP_001192179 NM_001205251 NP_001192180 NM_015256 NP_056071
Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Subcellular Location Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Tissue Specificity Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain. {ECO:0000269|PubMed:10548543}.
Top Pathways Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

ACSL6 (G-13) - sc-48003 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACSL6 (G-20) - sc-48004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACSL6 (G-20): sc-48004. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic staining of Purkinje cells, cells in granular layer and cells in molecular layer.

ACSL6 (H-70) - sc-134498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ACSL6 (H-70): sc-134498. Western blot analysis of ACSL6 expression in Jurkat (A), HEK293 (B), RT-4 (C), HL-60 (D), K-562 (E) and Raji (F) whole cell lysates.

ACSL6 (K-17) - sc-48005 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ACSL6 antibody - ab154094 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ACSL6 antibody (ab154094) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLane 3 : K562 whole cell lysateLane 4 : THP-1 whole cell lysateLane 5 : NC I-H929 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-ACSL6 antibody - ab199289 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ACSL6 antibody (ab199289) at 1/1000 dilutionLane 1 : Raji cell lysateLane 2 : K562 cell lysateLane 3 : HL60 cell lysate

Anti-ACSL6 antibody - ab74985 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ACSL6 antibody (ab74985) at 1/500 dilutionLane 1 : Extracts from COLO 205 cellsLane 2 : Extracts from Jurkat cellsLane 3 : Extracts from COLO 205 cells plus 5µg immunizing peptideLysates/proteins at 5 µg per lane.

Anti-ACSL6 Antibody (Internal, FITC) - LS-C206366 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 Antibody (Internal, PE) - LS-C206367 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 Antibody (Internal, Azide-free, HRP) - LS-C207931 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 Antibody (C-Terminus) - LS-C201406 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Fetal Liver. ACSL6 antibody dilution 1.0 ug/ml.

Anti-ACSL6 Antibody (Internal) - LS-C326768 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 Antibody (aa193-242) - LS-C201420 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Fetal Kidney. ACSL6 antibody dilution 1.0 ug/ml.

Anti-ACSL6 Antibody (aa499-548) IHC-plus™ - LS-B9840 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ACSL6 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9840 concentration 10 ug/ml.

Anti-ACSL6 Antibody (aa240-270) - LS-C98513 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-ACSL6 Antibody (Asp531) - LS-C177382 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of ACSL6 (D531) pAb in paraffin-embedded human brain tissue.

Anti-ACSL6 Antibody (Internal, AP) - LS-C206363 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 Antibody (Internal, APC) - LS-C206364 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 Antibody (Internal, Biotin) - LS-C206365 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

ACSL6 Antibody - NBP1-89269 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ACSL6 Antibody [NBP1-89269] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

ACSL6 Antibody - NBP2-15253 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ACSL6 Antibody [NBP2-15253] - A. 30 ug Jurkat whole cell lysate/extract, B. 30 ug Raji whole cell lysate/extract, C. 30 ug K562 whole cell lysate/extract. D. 30 ug THP-1 whole cell lysate/extract E. 30 ug NCI-H929 whole cell lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000

Anti-ACSL6 antibody produced in rabbit - SAB4500971 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ACSL6: <B>Cat. No. SAB4500971</B>: Immunoblotting analysis of extracts from COLO/Jurkat cells, using Anti-ACSL6 antibody. The lane on the left was treated with the Anti-ACSL6 antibody. The lane on the right (negative control) was treated with both Anti-ACSL6 antibody and the synthesized immunogen peptide.

ANTI-FACL6 (CENTER) antibody produced in rabbit - SAB1307086 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal

Anti-ACSL6 antibody produced in rabbit - HPA040470 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACSL6: <B>Cat. No. HPA040470</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

ACSL6 Antibody - C-terminal region (ARP41858_P050) - ARP41858_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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