Gene Symbol | PLA2G10 |
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Entrez Gene | 8399 |
Alt Symbol | GXPLA2, GXSPLA2, SPLA2 |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group X |
Other Description | GX sPLA2|group 10 secretory phospholipase A2|group X secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 10|sPLA2-X |
Swissprots | O15496 Q14DU3 Q6NT23 |
Accessions | CCQ43219 EAW85104 O15496 BC069539 AAH69539 BC106731 AAI06732 BC106732 AAI06733 BC111804 AAI11805 CR456885 CAG33166 U95301 AAB64410 XM_011522695 XP_011520997 XM_011522696 XP_011520998 XM_011522697 XP_011520999 XM_011522698 XP_011521000 XM_011546724 XP_011545026 XM_011546725 XP_011545027 XM_011546726 XP_011545028 XM_011546727 XP_011545029 NM_003561 NP_003552 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine. |
Subcellular Location | Secreted. |
Tissue Specificity | Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
group X sPLA 2 (E-4) - sc-514324 from Santa Cruz Biotechnology
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group X sPLA 2 (H-75) - sc-50381 from Santa Cruz Biotechnology
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group X sPLA 2 (L-13) - sc-22966 from Santa Cruz Biotechnology
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group X sPLA 2 (N-15) - sc-22965 from Santa Cruz Biotechnology
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Anti-Phospholipase A2 X antibody - ab47111 from Abcam
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Anti-Phospholipase A2 X antibody - ab168671 from Abcam
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Anti-Phospholipase A2 X antibody [EPR11202] - ab166634 from Abcam
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Anti-PLA2G10 Antibody (clone 5G11) - LS-C198554 from LifeSpan Bioscience
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PLA2G10 Antibody - NBP1-93706 from Novus Biologicals
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Phospholipase A2 X Antibody - H00008399-D01P from Novus Biologicals
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Phospholipase A2 X Antibody (5G11) - H00008399-M01-100ug from Novus Biologicals
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Monoclonal Anti-PLA2G10 antibody produced in mouse - SAB1412766 from Sigma-Aldrich
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Anti-PLA2G10 antibody produced in mouse - SAB1406658 from Sigma-Aldrich
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Anti-PLA2G10 antibody produced in rabbit - HPA041893 from Sigma-Aldrich
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PLA2G10 antibody - H00008399-B01P from Acris Antibodies
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PLA2G10 antibody - H00008399-D01P from Acris Antibodies
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PLA2G10 antibody - H00008399-M01 from Acris Antibodies
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Mouse Anti-Human PLA2G10 - 101-11271 from RayBiotech
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PLA2G10 antibody - 19502-1-AP from Proteintech Group
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sPLA2-X, Polyclonal Antibody - MBS619442 from MyBioSource
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Rabbit Anti-Human PLA2G10 Polyclonal Antibody - DPABH-07369 from Creative Diagnostics
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Monoclonal Antibody to Phospholipase A2, Group X (PLA2G10) - MAD833Hu21 from Uscn Life Science Inc.
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Polyclonal Antibody to Phospholipase A2, Group X (PLA2G10) - PAD833Hu01 from Uscn Life Science Inc.
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Rabbit Anti-Human PLA2G10 Polyclonal antibody - CABT-31320RH from Creative Diagnostics
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Anti-PLA2G10 monoclonal antibody, clone 6H22 - DCABH-16432 from Creative Diagnostics
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