SERPING1

Gene Symbol	SERPING1
Entrez Gene	710
Alt Symbol	C1IN, C1INH, C1NH, HAE1, HAE2
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Other Description	C1 esterase inhibitor|C1-inhibiting factor|complement component 1 inhibitor|plasma protease C1 inhibitor|serine/cysteine proteinase inhibitor clade G member 1|serpin G1
Swissprots	Q7Z455 Q9UCF9 B4E1F0 B2R6L5 Q96FE0 A6NMU0 B4E1H2 Q9UC49 Q59EI5 A8KAI9 Q16304 Q547W3 P05155
Accessions	AAA53096 AAB33044 AAM21515 AAQ19269 AAW69393 CAA30314 CAA38358 EAW73762 EAW73763 EAW73764 P05155 AB209826 BAD93063 AK293054 BAF85743 AK303809 BAG64762 AK303840 BAG64784 AK312626 BAG35512 AL703442 AY732485 AAV33124 AY732486 AAV33125 BC011171 AAH11171 BQ183346 BT006966 AAP35612 DQ891799 ABM82725 DQ894982 ABM85908 GU727623 ADU87625 M13203 AAA51849 M13656 AAB59387 M13690 AAA35613 M14036 AAA51848 X07577 CAA30469 NM_000062 NP_000053 NM_001032295 NP_001027466
Function	Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. {ECO:0000269|PubMed:8495195}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human C1 Inactivator protein fragment - ab176039 from Abcam Category Protein Prices $110.00, $179.00 Sizes 50 µg, 200 µg Source CHO Species Human

Human C1 Inactivator full length protein - ab183265 from Abcam Category Protein Prices $609.00 Sizes 1 mg Source Native Species Human

Human C1 Inactivator full length protein - ab140591 from Abcam Category Protein Prices $345.00 Sizes 100 µg Source E. coli Species Human

Human C1 Inactivator full length protein - ab152082 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human C1 Inactivator full length protein - ab90388 from Abcam Category Protein Prices $356.00 Sizes 1 mg Source Native Species Human

Human C1 Inactivator full length protein - ab77856 from Abcam Category Protein Prices $356.00 Sizes 1 mg Source Native Species Human

SERPING1 / C1 Inhibitor Antibody Blocking Peptide - LS-E8373 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Serpin G1/C1 Inhibitor Protein - H00000710-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Serpin G1/C1 Inhibitor Protein - NBP2-23463 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Species Human

SERPING1-Antibody-Center-Blocking-Peptide - BP6673b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

C1 Inhibitor recombinant protein - GTX53819 from GeneTex Category Protein Prices $219.00 Sizes 250 μg Source CHO cells

Human Serpin G1/C1 Inhibitor (Plasma), CF - 2488-PI-200 from R&D Systems Category Protein Source Human plasma-derived

Recombinant Mouse Plasma protease C1 inhibitor (OPCA00220) - OPCA00220 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Mouse

C1 Esterase Inhibitor Protein (OPMA04239) - OPMA04239 from Aviva Systems Biology Category Protein Prices $200.00 Sizes 1 mg

Human Serpin G1 protein - orb49650 from Biorbyt Category Protein Prices $306.00, $680.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human SERPING1 protein - orb191064 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Species Human

Human SERPING1 protein - orb169278 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Species Human

SERPING1 protein (His tag) - 80R-2718 from Fitzgerald Category Protein Prices $365.00 Sizes 100 µg Source E.coli

Human Complement 1 Inhibitor Protein - abx066043 from Abbexa Category Protein Source E.coli Species Human

SERPING1 Protein - abx069767 from Abbexa Category Protein Source Human Plasma

SERPING1 / C1 Inhibitor - AR31106PU-N from Acris Antibodies Category Protein Prices $235.00 Sizes 200 µg Source CHO cells Species Human

SERPING1 / C1 Inhibitor - AR31106PU-S from Acris Antibodies Category Protein Prices $135.00 Sizes 50 µg Source CHO cells Species Human

SERPING1 / C1 Inhibitor (23-500, His-tag) - AR50838PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

SERPING1 / C1 Inhibitor (23-500, His-tag) - AR50838PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

SERPING1 / C1 Inhibitor - BA1075 from Acris Antibodies Category Protein Prices $255.00 Sizes 1 mg Source Plasma Species Human

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