SERPING1

Gene Symbol	SERPING1
Entrez Gene	710
Alt Symbol	C1IN, C1INH, C1NH, HAE1, HAE2
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Other Description	C1 esterase inhibitor|C1-inhibiting factor|complement component 1 inhibitor|plasma protease C1 inhibitor|serine/cysteine proteinase inhibitor clade G member 1|serpin G1
Swissprots	Q7Z455 Q9UCF9 B4E1F0 B2R6L5 Q96FE0 A6NMU0 B4E1H2 Q9UC49 Q59EI5 A8KAI9 Q16304 Q547W3 P05155
Accessions	AAA53096 AAB33044 AAM21515 AAQ19269 AAW69393 CAA30314 CAA38358 EAW73762 EAW73763 EAW73764 P05155 AB209826 BAD93063 AK293054 BAF85743 AK303809 BAG64762 AK303840 BAG64784 AK312626 BAG35512 AL703442 AY732485 AAV33124 AY732486 AAV33125 BC011171 AAH11171 BQ183346 BT006966 AAP35612 DQ891799 ABM82725 DQ894982 ABM85908 GU727623 ADU87625 M13203 AAA51849 M13656 AAB59387 M13690 AAA35613 M14036 AAA51848 X07577 CAA30469 NM_000062 NP_000053 NM_001032295 NP_001027466
Function	Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. {ECO:0000269|PubMed:8495195}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse SERPING1 / C1 Inhibitor ELISA Kit (Sandwich ELISA) - LS-F5229 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 15.6 ng/ml Range 0.781-50 ng/ml

Human SERPING1 / C1 Inhibitor ELISA Kit (Sandwich ELISA) - LS-F4607 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.35 ng/ml Range 0.781-50 ng/ml

Rat SERPING1 / C1 Inhibitor EIA Kit - LS-F6260 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 2.26 ng/ml Range 6.17 - 500 ng/ml

Human SERPING1 / C1 Inhibitor ELISA Kit (Sandwich ELISA) - LS-F11702 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.781-50 ng/ml

Human Serpin G1/C1 Inhibitor DuoSet ELISA - DY2488-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 156.00 - 10,000 pg/mL

Human C1INH ELISA Kit - abx054430 from Abbexa Category ELISA Kit

Human C1INH ELISA Kit - abx150849 from Abbexa Category ELISA Kit Sensitivity 0.38 ng/ml Range 0.781 ng/ml - 50 ng/ml

Complement 1 Inhibitor, C1INH, Human, ELISA Kit - E-EL-H0802 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

Complement 1 Inhibitor (C1INH), Human, ELISA Kit - SEA235Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.33ng/mL Range 0.78-50ng/mL

Plasma protease C1 inhibitor (SERPING1), Human, ELISA Kit - CSB-EL021086HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 4.7 ng/ml Range 18.75ng/ml-1200ng/ml

Plasma protease C1 inhibitor, SERPING1, Human, ELISA Kit - E0235h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.312-20 ng/mL

Complement 1 Inhibitor, C1INH, Mouse, ELISA Kit - E-EL-M0329 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Complement 1 Inhibitor, C1INH, Rat, ELISA Kit - E-EL-R0246 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500ng/mL

Complement 1 Inhibitor, C1INH, Rabbit, ELISA Kit - E-EL-RB2124 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Complement 1 Inhibitor, C1INH, Chicken, ELISA Kit - E-EL-Ch1450 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Complement 1 Inhibitor, C1INH, Porcine, ELISA Kit - E-EL-P0190 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Complement 1 Inhibitor, C1INH, Sheep, ELISA Kit - E-EL-S0819 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Complement 1 Inhibitor, C1INH, Monkey, ELISA Kit - E-EL-MK0904 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Complement 1 Inhibitor (C1INH), Human, CLIA Kit - SCA235Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 0.26ng/mL Range 0.78 -50ng/mL

SERPING1 (Human) IP-WB Antibody Pair - H00000710-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SERPING1 (Human) Matched Antibody Pair - H00000710-AP51 from Acris Antibodies Category Antibody Pair Prices $770.00 Sizes 1 set

Custom Human SERPING1 ELISA - ELH-SERPING1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human C1INH ELISA Kit - HC0360 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

ELISA Kit for Complement 1 Inhibitor (C1INH) - SEA235Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.31ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

CLIA Kit for Complement 1 Inhibitor (C1INH) - SCA235Hu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.03ng/mL. Range 0.069-50ng/mL The standard curve concentrations used for the CLIA’s were 50ng/mL, 16.667ng/mL, 5.556ng/mL, 1.852ng/mL, 0.617ng/mL, 0.206ng/mL, 0.069ng/mL

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