Ace2

Gene Symbol Ace2
Entrez Gene 70008
Alt Symbol 2010305L05Rik
Species Mouse
Gene Type protein-coding
Description angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Other Description ACE-related carboxypeptidase|angiotensin I converting enzyme 2|angiotensin-converting enzyme 2
Swissprots Q8R0I0 Q99N70 Q99N71
Accessions EDL40761 Q8R0I0 AB053181 BAB40431 AB053182 BAB40432 AI115946 AK008530 BAB25723 AK135357 BAE22502 AK141604 BAE24759 BC026801 AAH26801 BY722909 EF408739 ABN80105 EF408740 ABN80106 GQ262785 ACT66269 NM_001130513 NP_001123985 NM_027286 NP_081562
Function Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury. {ECO:0000269|PubMed:12075344, ECO:0000269|PubMed:12967627, ECO:0000269|PubMed:16001071}.
Subcellular Location Processed angiotensin-converting enzyme 2: Secreted {ECO:0000250}.
Tissue Specificity Expressed in heart, kidney and forebrain (at protein level). Ubiquitously expressed, with highest levels in ileum, kidney and lung. In lung, expressed on vascular endothelial and airway epithelial cells. {ECO:0000269|PubMed:12487024, ECO:0000269|PubMed:15949646, ECO:0000269|PubMed:16001071}.
Top Pathways Protein digestion and absorption, Renin-angiotensin system

ACE2 CRISPR/Cas9 KO Plasmid (m) - sc-427594 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 HDR Plasmid (m) - sc-427594-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 Double Nickase Plasmid (m) - sc-427594-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 Double Nickase Plasmid (m2) - sc-427594-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 CRISPR Activation Plasmid (m) - sc-427594-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 CRISPR Activation Plasmid (m2) - sc-427594-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 Lentiviral Activation Particles (m) - sc-427594-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 Lentiviral Activation Particles (m2) - sc-427594-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACE2 siRNA (m) - sc-41401 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ACE2 shRNA Plasmid (m) - sc-41401-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ACE2 shRNA (m) Lentiviral Particles - sc-41401-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN26144 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26144 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACE2 siRNA (Mouse) - CRM8132 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

ACE2 - MBS829658 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse ACE2 (NM_027286.4) - SHH230222 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse ACE2 siRNA - orb287608 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

ACE2 shRNA Plasmid (Mouse) - CHM8132 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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