Gene Symbol | THAP11 |
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Entrez Gene | 57215 |
Alt Symbol | CTG-B43a, CTG-B45d, HRIHFB2206, RONIN |
Species | Human |
Gene Type | protein-coding |
Description | THAP domain containing 11 |
Other Description | THAP domain-containing protein 11 |
Swissprots | O94795 Q96EK4 A4UCT5 A8K002 |
Accessions | EAW83180 Q96EK4 AB015338 BAA34796 AK289367 BAF82056 BC012182 AAH12182 BI261822 BQ898449 DQ892600 ABM83526 DQ895831 ABM86757 EF036502 ABO65088 EU869208 ACG50140 L10378 L10379 NM_020457 NP_065190 |
Function | Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9853615}. Cytoplasm {ECO:0000250}. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus. {ECO:0000250}. |
THAP11 CRISPR/Cas9 KO Plasmid (h) - sc-410604 from Santa Cruz Biotechnology
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THAP11 HDR Plasmid (h) - sc-410604-HDR from Santa Cruz Biotechnology
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THAP11 Double Nickase Plasmid (h) - sc-410604-NIC from Santa Cruz Biotechnology
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THAP11 Double Nickase Plasmid (h2) - sc-410604-NIC-2 from Santa Cruz Biotechnology
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THAP11 CRISPR Activation Plasmid (h) - sc-410604-ACT from Santa Cruz Biotechnology
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THAP11 CRISPR Activation Plasmid (h2) - sc-410604-ACT-2 from Santa Cruz Biotechnology
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THAP11 Lentiviral Activation Particles (h) - sc-410604-LAC from Santa Cruz Biotechnology
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THAP11 Lentiviral Activation Particles (h2) - sc-410604-LAC-2 from Santa Cruz Biotechnology
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THAP11 siRNA (h) - sc-93328 from Santa Cruz Biotechnology
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THAP11 shRNA Plasmid (h) - sc-93328-SH from Santa Cruz Biotechnology
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THAP11 shRNA (h) Lentiviral Particles - sc-93328-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU144561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21293 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21293 from Sigma-Aldrich
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THAP11 siRNA (Human) - CRJ1400 from Cohesion Biosciences
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THAP11 RNAi - H00057215-R01 from Novus Biologicals
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THAP11 - MBS8214930 from MyBioSource
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shRNA set against Human THAP11 (NM_020457.2) - SHH426692 from Creative biogene
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Human THAP11 siRNA - orb271901 from Biorbyt
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THAP11 shRNA Plasmid (Human) - CHJ1400 from Cohesion Biosciences
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THAP11 miRNA 3'UTR clone - MiUTR1H-10372 from Creative biogene
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