Gene Symbol |
THAP11
|
Entrez Gene |
57215
|
Alt Symbol |
CTG-B43a, CTG-B45d, HRIHFB2206, RONIN
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
THAP domain containing 11
|
Other Description |
THAP domain-containing protein 11
|
Swissprots |
O94795 Q96EK4 A4UCT5 A8K002
|
Accessions |
EAW83180 Q96EK4 AB015338 BAA34796 AK289367 BAF82056 BC012182 AAH12182 BI261822 BQ898449 DQ892600 ABM83526 DQ895831 ABM86757 EF036502 ABO65088 EU869208 ACG50140 L10378 L10379 NM_020457 NP_065190
|
Function |
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:9853615}. Cytoplasm {ECO:0000250}. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus. {ECO:0000250}.
|