YBX2

Gene Symbol YBX2
Entrez Gene 51087
Alt Symbol CONTRIN, CSDA3, DBPC, MSY2
Species Human
Gene Type protein-coding
Description Y box binding protein 2
Other Description DNA-binding protein C|MSY2 homolog|Y-box-binding protein 2|germ cell specific Y-box binding protein|germ cell-specific Y-box-binding protein
Swissprots Q8N4P0 D3DTP1 Q9Y2T7
Accessions EAW90223 EAW90224 EAW90225 Q9Y2T7 AB208818 BAD92055 AF096834 AAD30662 AI805280 AK092747 AK315035 BAG37519 BC033800 AAH33800 BC047760 AAH47760 DB065912 NM_015982 NP_057066
Function Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16479255}. Nucleus {ECO:0000269|PubMed:16479255}.
Tissue Specificity Expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Also observed placental trophoblasts, as well as in vascular smooth muscle cells in the pulmonary artery, myocardium, and skeletal muscle. Undetectable in epithelial cells in respiratory, gastrointestinal, and urogenital tracts. Up-regulated in various carcinomas and germ cell tumors (at protein level). {ECO:0000269|PubMed:10100484, ECO:0000269|PubMed:16479255}.

MSY2 CRISPR/Cas9 KO Plasmid (h) - sc-405504 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 HDR Plasmid (h) - sc-405504-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 Double Nickase Plasmid (h) - sc-405504-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 Double Nickase Plasmid (h2) - sc-405504-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 CRISPR Activation Plasmid (h) - sc-405504-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 CRISPR Activation Plasmid (h2) - sc-405504-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 Lentiviral Activation Particles (h) - sc-405504-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 Lentiviral Activation Particles (h2) - sc-405504-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSY2 siRNA (h) - sc-38630 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSY2 shRNA Plasmid (h) - sc-38630-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSY2 shRNA (h) Lentiviral Particles - sc-38630-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSY2 RNAi - H00051087-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN23000 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23000 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

YBX2 siRNA (Human) - CRH9509 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

YBX2 - MBS8212094 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human YBX2 (NM_015982.3) - SHH448296 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human YBX2(NM_015982.3) - SHL139662 from Creative biogene

Category siRNA
Species Reactivities Human

YBX2 shRNA Plasmid (Human) - CHH9509 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

YBX2 miRNA 3'UTR clone - MiUTR1H-11332 from Creative biogene

Species Reactivities Human
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