Gene Symbol | HIST1H3F |
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Entrez Gene | 8968 |
Alt Symbol | H3/i, H3FI |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H3f |
Other Description | H3 histone family, member I|histone 1, H3f|histone H3.1|histone H3/i |
Swissprots | Q71DJ3 Q6NWP8 A5PLR1 Q6NWP9 A0PJT7 P68431 Q93081 Q6NXU4 Q6ISV8 |
Accessions | AAN10056 CAB02548 EAW55551 AK314142 BAG36832 BC062305 BC067492 AAH67492 BC069818 AAH69818 BC096131 AAH96131 CR541983 CAG46780 CR542011 CAG46808 NM_021018 NP_066298 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer |
Histone cluster 1 H3F CRISPR/Cas9 KO Plasmid (h) - sc-411229 from Santa Cruz Biotechnology
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Histone cluster 1 H3F HDR Plasmid (h) - sc-411229-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H3F Double Nickase Plasmid (h) - sc-411229-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H3F Double Nickase Plasmid (h2) - sc-411229-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H3F CRISPR Activation Plasmid (h) - sc-411229-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H3F CRISPR Activation Plasmid (h2) - sc-411229-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H3F Lentiviral Activation Particles (h) - sc-411229-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H3F Lentiviral Activation Particles (h2) - sc-411229-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H3F siRNA (h) - sc-105491 from Santa Cruz Biotechnology
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Histone cluster 1 H3F shRNA Plasmid (h) - sc-105491-SH from Santa Cruz Biotechnology
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Histone cluster 1 H3F shRNA (h) Lentiviral Particles - sc-105491-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10088 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10088 from Sigma-Aldrich
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HIST1H3F siRNA (Human) - CRH5918 from Cohesion Biosciences
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shRNA set against Human HIST1H3F (NM_021018.2) - SHH312733 from Creative biogene
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HIST1H3F shRNA Plasmid (Human) - CHH5918 from Cohesion Biosciences
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HIST1H3F miRNA 3'UTR clone - MiUTR1H-04548 from Creative biogene
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