| Gene Symbol |
HIST1H3F
|
| Entrez Gene |
8968
|
| Alt Symbol |
H3/i, H3FI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H3f
|
| Other Description |
H3 histone family, member I|histone 1, H3f|histone H3.1|histone H3/i
|
| Swissprots |
Q71DJ3 Q6NWP8 A5PLR1 Q6NWP9 A0PJT7 P68431 Q93081 Q6NXU4 Q6ISV8
|
| Accessions |
AAN10056 CAB02548 EAW55551 AK314142 BAG36832 BC062305 BC067492 AAH67492 BC069818 AAH69818 BC096131 AAH96131 CR541983 CAG46780 CR542011 CAG46808 NM_021018 NP_066298
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer
|