EIF2S2

Gene Symbol EIF2S2
Entrez Gene 8894
Alt Symbol EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
Other Description eukaryotic translation initiation factor 2 subunit 2|eukaryotic translation initiation factor 2 subunit beta|protein phosphatase 1, regulatory subunit 67
Swissprots Q9BVU0 P20042 Q9UJE4
Accessions AAD19864 EAW76284 EAW76285 EAW76286 P20042 AB208966 BAD92203 AB451237 BAG70051 AB451362 BAG70176 AK313025 BAG35860 BC000461 AAH00461 BC000934 AAH00934 BC007888 AAH07888 BC070316 BC107588 AAI07589 BT009795 AAP88797 BX648379 CR456734 CAG33015 DQ891005 ABM81931 DQ894184 ABM85110 M29536 AAA52383 XM_005260605 XP_005260662 NM_003908 NP_003899
Function eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Top Pathways RNA transport

eIF2β siRNA (h) - sc-35270 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF2β shRNA Plasmid (h) - sc-35270-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF2β shRNA (h) Lentiviral Particles - sc-35270-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EIF2 beta RNAi - H00008894-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110181 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7755 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7755 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09751 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09751

EIF2S2 siRNA (Human) - CRH5879 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EIF2S2 - MBS8222514 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EIF2S2 (NM_003908.3) - SHH284381 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human EIF2S2(NM_003908.3) - SHH029071 from Creative biogene

Category siRNA
Species Reactivities Human

Human EIF2S2 siRNA - orb266381 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EIF2S2 shRNA Plasmid (Human) - CHH5879 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EIF2S2 miRNA 3'UTR clone - MiUTR1H-03160 from Creative biogene

Species Reactivities Human
Search more