AGRP

Gene Symbol	AGRP
Entrez Gene	181
Alt Symbol	AGRT, ART, ASIP2
Species	Human
Gene Type	protein-coding
Description	agouti related neuropeptide
Other Description	agouti related protein homolog|agouti-related protein
Swissprots	Q2TBD9 O15459 O00253
Accessions	AAK96256 AAL09457 ABC88473 DAA06531 EAW83137 O00253 BC110443 AAI10444 U88063 AAB52240 U89485 AAB68621 XM_011522927 XP_011521229 NM_001138 NP_001129
Function	Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. {ECO:0000250, ECO:0000269|PubMed:10371151, ECO:0000269|PubMed:11145747, ECO:0000269|PubMed:15927146, ECO:0000269|PubMed:17041250, ECO:0000269|PubMed:9892020}.
Subcellular Location	Secreted {ECO:0000269|PubMed:15927146}. Golgi apparatus lumen {ECO:0000269|PubMed:15927146}.
Tissue Specificity	Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Top Pathways	Adipocytokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat AGRP ELISA Kit (Sandwich ELISA) - LS-F6405 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 3.5 pg/ml Range 6.144-600 pg/ml

Human AGRP ELISA Kit (Sandwich ELISA) - LS-F4548 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 3.1 pg/ml Range 6.144-600 pg/ml

Human AGRP ELISA Kit (Sandwich ELISA) - LS-F28 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 6.144 pg/ml Range 6.144-600 pg/ml

Human AGRP ELISA Kit (Sandwich ELISA) - LS-F673 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 6.144-600 pg/ml

Mouse AGRP ELISA Kit - LS-F7689 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 3.4 pg/ml Range 7.813 - 500 pg/ml

Human AGRP ELISA Kit (Sandwich ELISA) - LS-F10093 from LifeSpan Bioscience Category ELISA Kit Prices $510.00 Sizes 1 plate Sensitivity 0.002 pg/ml Range 6.144-600 pg/ml

Human AGRP ELISA Kit (Sandwich ELISA) - LS-F10768 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 Range 6.144-600 pg/ml

Bovine AGRP ELISA Kit (Sandwich ELISA) - LS-F10769 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 78 Range 6.144-600 pg/ml

Human AGRP / Agouti-related Protein ELISA Kit - RAB0529 from Sigma-Aldrich Category ELISA Kit Prices $633.00 Sizes 1 kt Sensitivity 6 pg/ml

Human AgRP Quantikine ELISA Kit - DAGR00 from R&D Systems Category ELISA Kit Prices $509.00 Sizes 1 kit Sensitivity 2.68 pg/mL Range 7.8 - 500 pg/mL (Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Urine)

Human AgRP DuoSet ELISA - DY704 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

AgRP ELISA Kit (Human) : 96 Wells (OKAG00192) - OKAG00192 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 125 pg/mL Range 125-4,000 pg/mL

Human AgRP ELISA kit - orb78657 from Biorbyt Category ELISA Kit Prices $740.00, $1,258.00, $2,678.00 Sizes 96 well, 192 assays, 480 assays Sensitivity 6 pg/ml Range 6 pg/ml - 1500 pg/ml

Human AGRP ELISA Kit - abx150591 from Abbexa Category ELISA Kit Sensitivity 3.1 pg/ml Range 7.813 pg/ml - 500 pg/ml

Agouti Related Protein (AGRP), Human, ELISA Kit - SEB302Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 2.7pg/mL Range 7.8-500pg/mL

Agouti Related Protein, AGRP, Human, ELISA Kit - CSB-E09299h from ARP American Research Products Category ELISA Kit Prices $265.00, $395.00, $396.00, $397.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml -2000 pg/ml

Agouti-related protein, AGRP, Human, ELISA Kit - E1302h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 15.6-1000 pg/mL

Agouti Related Protein, AgRP, Human, ELISA Kit - E-EL-H0005 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Agouti Related Protein, AgRP, Mouse, ELISA Kit - E-EL-M1356 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Agouti Related Protein, AgRP, Rat, ELISA Kit - E-EL-R1434 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Human AgRP ELISA - ELH-AgRP from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 6 pg/ml Range 6 pg/ml - 1500 pg/ml

Human AGRP ELISA Kit - HA0515 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human ART ELISA Kit - HA0039 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ART ELISA Kit - AA0039 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine AGRP ELISA Kit - AA0515 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

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