Gene Symbol | UBE2E2 |
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Entrez Gene | 7325 |
Alt Symbol | UBCH8 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2E 2 |
Other Description | ubiquitin carrier protein E2|ubiquitin-conjugating enzyme E2 E2|ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 2 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E2 |
Swissprots | Q96LR5 |
Accessions | CCQ43860 EAW64321 EAW64322 EAW64323 EAW64324 EAW64325 Q96LR5 AK057886 BAB71605 AK307075 BC022332 AAH22332 CB851345 XM_005265432 XP_005265489 XM_005265433 XP_005265490 XM_005265434 XP_005265491 XM_011534074 XP_011532376 XM_011534075 XP_011532377 XM_011534076 XP_011532378 NM_152653 NP_689866 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein. {ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:20133869, ECO:0000269|PubMed:9371400}. |
Top Pathways | Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum |
UBE2E2 CRISPR/Cas9 KO Plasmid (h) - sc-406437 from Santa Cruz Biotechnology
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UBE2E2 HDR Plasmid (h) - sc-406437-HDR from Santa Cruz Biotechnology
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UBE2E2 Double Nickase Plasmid (h) - sc-406437-NIC from Santa Cruz Biotechnology
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UBE2E2 Double Nickase Plasmid (h2) - sc-406437-NIC-2 from Santa Cruz Biotechnology
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UBE2E2 CRISPR Activation Plasmid (h) - sc-406437-ACT from Santa Cruz Biotechnology
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UBE2E2 CRISPR Activation Plasmid (h2) - sc-406437-ACT-2 from Santa Cruz Biotechnology
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UBE2E2 Lentiviral Activation Particles (h) - sc-406437-LAC from Santa Cruz Biotechnology
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UBE2E2 Lentiviral Activation Particles (h2) - sc-406437-LAC-2 from Santa Cruz Biotechnology
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UBE2E2 siRNA (h) - sc-106656 from Santa Cruz Biotechnology
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UBE2E2 shRNA Plasmid (h) - sc-106656-SH from Santa Cruz Biotechnology
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UBE2E2 shRNA (h) Lentiviral Particles - sc-106656-V from Santa Cruz Biotechnology
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UBE2E2 RNAi - H00007325-R01 from Novus Biologicals
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MISSION® esiRNA - EHU041931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22362 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22362 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06222 from Sigma-Aldrich
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UBE2E2 siRNA (Human) - CRH5008 from Cohesion Biosciences
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UBE2E2 - MBS8228212 from MyBioSource
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UBE2E2 CRISPR/Cas9 KO Plasmid (h2) - sc-406437-KO-2 from Santa Cruz Biotechnology
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UBE2E2 HDR Plasmid (h2) - sc-406437-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human UBE2E2 (NM_152653.3) - SHH438940 from Creative biogene
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shRNA set against Human UBE2E2(NM_152653.3) - SHL110836 from Creative biogene
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Human UBE2E2 siRNA - orb265510 from Biorbyt
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UBE2E2 shRNA Plasmid (Human) - CHH5008 from Cohesion Biosciences
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UBE2E2 miRNA 3'UTR clone - MiUTR1H-10946 from Creative biogene
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