| Gene Symbol |
UBE2E2
|
| Entrez Gene |
7325
|
| Alt Symbol |
UBCH8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin-conjugating enzyme E2E 2
|
| Other Description |
ubiquitin carrier protein E2|ubiquitin-conjugating enzyme E2 E2|ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 2 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E2
|
| Swissprots |
Q96LR5
|
| Accessions |
CCQ43860 EAW64321 EAW64322 EAW64323 EAW64324 EAW64325 Q96LR5 AK057886 BAB71605 AK307075 BC022332 AAH22332 CB851345 XM_005265432 XP_005265489 XM_005265433 XP_005265490 XM_005265434 XP_005265491 XM_011534074 XP_011532376 XM_011534075 XP_011532377 XM_011534076 XP_011532378 NM_152653 NP_689866
|
| Function |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein. {ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:20133869, ECO:0000269|PubMed:9371400}.
|
| Top Pathways |
Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum
|