Gene Symbol | GTF2F2 |
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Entrez Gene | 2963 |
Alt Symbol | BTF4, RAP30, TF2F2, TFIIF |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIF, polypeptide 2, 30kDa |
Other Description | ATP-dependent helicase GTF2F2|TFIIF-beta|general transcription factor IIF 30 kDa subunit|general transcription factor IIF subunit 2|transcription initiation factor IIF subunit beta|transcription initiation factor RAP30 |
Swissprots | Q5W0H3 P13984 A6NNS5 |
Accessions | EAX08726 EAX08727 EAX08728 EAX08729 P13984 AK291545 BAF84234 BC001771 AAH01771 BT019525 AAV38332 CA429230 CB124466 DB252856 EU831971 ACE87412 EU832064 ACE86726 X16901 CAA34775 X59745 CAA42419 XM_011535052 XP_011533354 XM_011535053 XP_011533355 NM_004128 NP_004119 |
Function | TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA- helicase activity. {ECO:0000269|PubMed:2477704}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10454543}. |
Top Pathways | Basal transcription factors |
TFIIF RAP 30 CRISPR/Cas9 KO Plasmid (h) - sc-416804 from Santa Cruz Biotechnology
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TFIIF RAP 30 HDR Plasmid (h) - sc-416804-HDR from Santa Cruz Biotechnology
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TFIIF RAP 30 Double Nickase Plasmid (h) - sc-416804-NIC from Santa Cruz Biotechnology
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TFIIF RAP 30 Double Nickase Plasmid (h2) - sc-416804-NIC-2 from Santa Cruz Biotechnology
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TFIIF RAP 30 CRISPR Activation Plasmid (h) - sc-416804-ACT from Santa Cruz Biotechnology
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TFIIF RAP 30 CRISPR Activation Plasmid (h2) - sc-416804-ACT-2 from Santa Cruz Biotechnology
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TFIIF RAP 30 Lentiviral Activation Particles (h) - sc-416804-LAC from Santa Cruz Biotechnology
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TFIIF RAP 30 Lentiviral Activation Particles (h2) - sc-416804-LAC-2 from Santa Cruz Biotechnology
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TFIIF RAP 30 siRNA (h) - sc-38521 from Santa Cruz Biotechnology
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TFIIF RAP 30 shRNA Plasmid (h) - sc-38521-SH from Santa Cruz Biotechnology
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TFIIF RAP 30 shRNA (h) Lentiviral Particles - sc-38521-V from Santa Cruz Biotechnology
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RAP74 RNAi - H00002963-R01 from Novus Biologicals
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MISSION® esiRNA - EHU097441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9760 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9760 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04471 from Sigma-Aldrich
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GTF2F2 siRNA (Human) - CRH2006 from Cohesion Biosciences
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GTF2F2 - MBS8226993 from MyBioSource
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shRNA set against Human GTF2F2 (NM_004128.2) - SHH308906 from Creative biogene
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Human GTF2F2 siRNA - orb262508 from Biorbyt
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GTF2F2 shRNA Plasmid (Human) - CHH2006 from Cohesion Biosciences
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GTF2F2 miRNA 3'UTR clone - MiUTR3H-02250 from Creative biogene
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