Gene Symbol |
GTF2F2
|
Entrez Gene |
2963
|
Alt Symbol |
BTF4, RAP30, TF2F2, TFIIF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
general transcription factor IIF, polypeptide 2, 30kDa
|
Other Description |
ATP-dependent helicase GTF2F2|TFIIF-beta|general transcription factor IIF 30 kDa subunit|general transcription factor IIF subunit 2|transcription initiation factor IIF subunit beta|transcription initiation factor RAP30
|
Swissprots |
Q5W0H3 P13984 A6NNS5
|
Accessions |
EAX08726 EAX08727 EAX08728 EAX08729 P13984 AK291545 BAF84234 BC001771 AAH01771 BT019525 AAV38332 CA429230 CB124466 DB252856 EU831971 ACE87412 EU832064 ACE86726 X16901 CAA34775 X59745 CAA42419 XM_011535052 XP_011533354 XM_011535053 XP_011533355 NM_004128 NP_004119
|
Function |
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA- helicase activity. {ECO:0000269|PubMed:2477704}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:10454543}.
|
Top Pathways |
Basal transcription factors
|