Gene Symbol | CPZ |
---|---|
Entrez Gene | 8532 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | carboxypeptidase Z |
Other Description | metallocarboxypeptidase Z |
Swissprots | Q96MX2 O00520 Q66K79 |
Accessions | EAW82332 EAW82333 EAW82334 EAW82335 Q66K79 AI270606 AK056317 BAB71147 AK127844 BAG54585 AW139378 BC006393 BC018913 BC080539 AAH80539 BF993977 BX338482 CV026874 DA050438 DA698835 DA704214 U83411 AAB58911 NM_001014447 NP_001014447 NM_001014448 NP_001014448 NM_003652 NP_003643 |
Function | Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. {ECO:0000269|PubMed:11766880, ECO:0000269|PubMed:12417617, ECO:0000269|PubMed:9099699}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10671522}. |
Tissue Specificity | In placenta, it is present within invasive trophoblasts and in the surrounding extracellular space. Also present in amnion cells, but is not readily apparent in the extracellular matrix of this cell type. Present in normal pituitary gland and neoplastic pituitary gland (especially POMC-, GH- and PRL-producing adenomas) (at protein level). Widely expressed. {ECO:0000269|PubMed:10671522, ECO:0000269|PubMed:12417617, ECO:0000269|PubMed:9099699}. |
Carboxypeptidase Z / CPZ Antibody Blocking Peptide - LS-E8277 from LifeSpan Bioscience
|
||||||||||
CPZ-Antibody-N-term-Blocking-Peptide - BP6546a from Abgent, a WuXi AppTec company
|
||||||||||
CPZ fusion protein - Ag8429 from Proteintech Group
|
||||||||||
Recombinant Human CPZ, His-tagged - CPZ-11548H from Creative Biomart
|
||||||||||
Recombinant Carboxypeptidase Z (CPZ) - RPF326Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Carboxypeptidase Z (CPZ) - RPF326Hu01 from Cloud-clone
|
||||||||||
Recombinant Human Carboxypeptidase Z(CPZ) - CSB-YP005931HU CSB-EP005931HU CSB-BP005931HU CSB-MP005931HU from Cusabio
|
||||||||||
Carboxypeptidase Z Protein (Recombinant) - abx166753 from Abbexa
|
||||||||||
Carboxypeptidase Z, Recombinant Protein - MBS2028856 from MyBioSource
|
||||||||||
Carboxypeptidase Z (CPZ), Recombinant Protein - MBS1464664 from MyBioSource
|
||||||||||
CPZ Peptide, Human - M34GP03604H from Creative Peptides
|
||||||||||
Recombinant Carboxypeptidase Z (CPZ) - RPU52270 from Biomatik
|
||||||||||
CPZ Recombinant Protein (OPCD02390) - OPCD02390 from Aviva Systems Biology
|
||||||||||