Gene Symbol | CPZ |
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Entrez Gene | 8532 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | carboxypeptidase Z |
Other Description | metallocarboxypeptidase Z |
Swissprots | Q96MX2 O00520 Q66K79 |
Accessions | EAW82332 EAW82333 EAW82334 EAW82335 Q66K79 AI270606 AK056317 BAB71147 AK127844 BAG54585 AW139378 BC006393 BC018913 BC080539 AAH80539 BF993977 BX338482 CV026874 DA050438 DA698835 DA704214 U83411 AAB58911 NM_001014447 NP_001014447 NM_001014448 NP_001014448 NM_003652 NP_003643 |
Function | Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. {ECO:0000269|PubMed:11766880, ECO:0000269|PubMed:12417617, ECO:0000269|PubMed:9099699}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10671522}. |
Tissue Specificity | In placenta, it is present within invasive trophoblasts and in the surrounding extracellular space. Also present in amnion cells, but is not readily apparent in the extracellular matrix of this cell type. Present in normal pituitary gland and neoplastic pituitary gland (especially POMC-, GH- and PRL-producing adenomas) (at protein level). Widely expressed. {ECO:0000269|PubMed:10671522, ECO:0000269|PubMed:12417617, ECO:0000269|PubMed:9099699}. |
CPZ (D-14) - sc-138216 from Santa Cruz Biotechnology
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CPZ (S-12) - sc-138218 from Santa Cruz Biotechnology
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Anti-Carboxypeptidase Z antibody - N-terminal - ab91180 from Abcam
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Anti-Carboxypeptidase Z / CPZ Antibody (N-Terminus) - LS-C99274 from LifeSpan Bioscience
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CPZ Antibody - NBP1-85944 from Novus Biologicals
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CPZ Antibody - NBP1-86369 from Novus Biologicals
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ANTI-CPZ(N-TERMINAL) antibody produced in rabbit - SAB1307109 from Sigma-Aldrich
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Anti-CPZ antibody produced in rabbit - HPA029082 from Sigma-Aldrich
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CPZ Antibody - N-terminal region (OAAB03550) - OAAB03550 from Aviva Systems Biology
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CPZ-Antibody-N-term - AP6546a from Abgent, a WuXi AppTec company
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CPZ antibody, N-term - GTX81852 from GeneTex
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CPZ Antibody (OAAF03446) - OAAF03446 from Aviva Systems Biology
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Chlorpromazine antibody - 20-1389 from Fitzgerald
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Carboxypeptidase Z antibody - 15944-1-AP from Acris Antibodies
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Carboxypeptidase Z (N-term) antibody - AP17239PU-N from Acris Antibodies
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CPZ antibody - 15944-1-AP from Proteintech Group
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Anti-CPZ antibody - STJ92458 from St John's Laboratory Ltd
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CPZ Antibody - EPP11857 from Elabscience
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Monoclonal Antibody to Carboxypeptidase Z (CPZ) - MAF326Hu21 from Uscn Life Science Inc.
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Polyclonal Antibody to Carboxypeptidase Z (CPZ) - PAF326Hu01 from Uscn Life Science Inc.
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Anti-Chlorpromazine polyclonal antibody - DPABY-815 from Creative Diagnostics
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CPZ Polyclonal Antibody - PA5-13484 from Thermo Fisher Scientific
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CPXM2-Specific, Polyclonal Antibody - MBS2517201 from MyBioSource
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CPZ, Polyclonal Antibody - MBS2522912 from MyBioSource
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CPZ, Polyclonal Antibody - MBS629411 from MyBioSource
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