FRZB

Gene Symbol	FRZB
Entrez Gene	2487
Alt Symbol	FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ
Species	Human
Gene Type	protein-coding
Description	frizzled-related protein
Other Description	frezzled|frizzled homolog-related|frizzled-related protein 1|sFRP-3|secreted frizzled-related protein 3
Swissprots	Q92765 O00181 Q99686
Accessions	AAX93117 AAY24241 ADL14515 EAX10958 Q92765 AK130009 AK312741 BAG35611 AU117730 BC027855 AAH27855 BE549700 BF058813 BT019883 AAV38686 DQ890944 ABM81870 DQ894106 ABM85032 U24163 AAC50736 U68057 AAC51217 U91903 AAB51298 NM_001463 NP_001454
Function	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FRZB full length protein - ab139224 from Abcam Category Protein Source E. coli Species Human

SFRP-3 / FRZB Antibody Blocking Peptide - LS-E19654 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SFRP-3 / FRZB Antibody Blocking Peptide - LS-E19655 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human sFRP-3/FRZB Protein - NBP2-23058 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human sFRP-3 - 192-SF-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala33-Asn325, with a C-terminal 10-His tag

Recombinant Human sFRP-3, CF - 192-SF-010/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala33-Asn325, with a C-terminal 10-His tag

Recombinant Human sFRP-3 - 7584-SF-025 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala33-Asn325

Recombinant Human sFRP-3, CF - 7584-SF-025/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala33-Asn325

Human FRZB protein - orb191059 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human FRZB protein (His Tag) - orb138885 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source Human Cells Species Human

FRZB Blocking Peptide - 33R-3859 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FRZB Blocking Peptide - 33R-9874 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FRZB protein (His tag) - 30R-2952 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

FRZB / SFRP3 (33-325, His-tag) - AR50712PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

FRZB / SFRP3 (33-325, His-tag) - AR50712PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

FRZB, 33-325aa, Human, His tag, E.coli - 01-P1888 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

FRZB fusion protein - Ag14403 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FRZB fusion protein - Ag3894 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human sFRP3 - BP001410-CA61 from Syd Labs Category Protein Source HEK 293 derived. Species Human

Human FRZB Recombinant Protein - GWB-PPAT50 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human FRZB, His-tagged - FRZB-7106H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human FRZB, His-tagged - FRZB-13010H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human FRZB, His tagged - FRZB-216H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human FRZB, His-tagged - FRZB-208H from Creative Biomart Category Protein Source NSO cells Species Human

Recombinant Human FRZB - FRZB-209H from Creative Biomart Category Protein Source NSO cells Species Human

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