SERPINB4

Gene Symbol SERPINB4
Entrez Gene 6318
Alt Symbol LEUPIN, PI11, SCCA-2, SCCA1, SCCA2
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade B (ovalbumin), member 4
Other Description SCCA2/SCCA1 fusion protein|peptidase inhibitor 11|protease inhibitor (leucine-serpin)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4|serpin B4|squamous cell carcinoma antigen 1|squamous cell carcinoma antigen 2
Swissprots A8K847 P48594
Accessions AAA92602 BAA75462 BAB21525 EAW63154 EAW63155 P48594 AB046400 BAB40773 AF461147 AAQ04771 AK292212 BAF84901 AY245780 AAO92271 AY245782 AAO92273 BC008399 BC017401 AAH17401 BU676816 DB118691 DQ892794 ABM83720 DQ896041 ABM87040 U19557 AAA97553 X89015 CAA61420 XM_011526138 XP_011524440 NM_002974 NP_002965 NM_175041 NP_778206
Function May act as a protease inhibitor to modulate the host immune response against tumor cells.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10956412}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Tissue Specificity Squamous cells.
Top Pathways Amoebiasis

SCCA1/2 CRISPR/Cas9 KO Plasmid (h) - sc-418018 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 HDR Plasmid (h) - sc-418018-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 Double Nickase Plasmid (h) - sc-418018-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 Double Nickase Plasmid (h2) - sc-418018-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 CRISPR Activation Plasmid (h) - sc-418018-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 CRISPR Activation Plasmid (h2) - sc-418018-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 Lentiviral Activation Particles (h) - sc-418018-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA1/2 Lentiviral Activation Particles (h2) - sc-418018-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SCCA2 siRNA (h) - sc-40951 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA2 shRNA Plasmid (h) - sc-40951-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SCCA2 shRNA (h) Lentiviral Particles - sc-40951-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19144 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19144 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04771 from Sigma-Aldrich

Category miRNA

SERPINB4 siRNA (Human) - CRH4256 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SERPINB4 - MBS8232079 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SERPINB4 (NM_002974.2) - SHH405208 from Creative biogene

Category siRNA
Species Reactivities Human

SERPINB4 shRNA Plasmid (Human) - CHH4256 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SERPINB4 miRNA 3'UTR clone - MiUTR1H-09302 from Creative biogene

Species Reactivities Human
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