| Gene Symbol |
SERPINB4
|
| Entrez Gene |
6318
|
| Alt Symbol |
LEUPIN, PI11, SCCA-2, SCCA1, SCCA2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serpin peptidase inhibitor, clade B (ovalbumin), member 4
|
| Other Description |
SCCA2/SCCA1 fusion protein|peptidase inhibitor 11|protease inhibitor (leucine-serpin)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4|serpin B4|squamous cell carcinoma antigen 1|squamous cell carcinoma antigen 2
|
| Swissprots |
A8K847 P48594
|
| Accessions |
AAA92602 BAA75462 BAB21525 EAW63154 EAW63155 P48594 AB046400 BAB40773 AF461147 AAQ04771 AK292212 BAF84901 AY245780 AAO92271 AY245782 AAO92273 BC008399 BC017401 AAH17401 BU676816 DB118691 DQ892794 ABM83720 DQ896041 ABM87040 U19557 AAA97553 X89015 CAA61420 XM_011526138 XP_011524440 NM_002974 NP_002965 NM_175041 NP_778206
|
| Function |
May act as a protease inhibitor to modulate the host immune response against tumor cells.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10956412}. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
|
| Tissue Specificity |
Squamous cells.
|
| Top Pathways |
Amoebiasis
|
![Western Blot: SERPINB4 Overexpression Lysate (Adult Normal) [NBL1-15847] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SERPINB4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1593_SERPINB4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15847-img0002.jpg)