Gene Symbol | GCDH |
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Entrez Gene | 2639 |
Alt Symbol | ACAD5, GCD |
Species | Human |
Gene Type | protein-coding |
Description | glutaryl-CoA dehydrogenase |
Other Description | glutaryl-CoA dehydrogenase, mitochondrial|glutaryl-Coenzyme A dehydrogenase |
Swissprots | O14719 A8K2Z2 Q92947 |
Accessions | AAB51174 AAC52079 AER00473 EAW84324 EAW84325 EAW84326 Q92947 AK098370 AK290407 BAF83096 AK296446 BAG59097 AK298772 BAG60914 AK300841 BAG62492 AK309892 AU135567 BC002579 AAH02579 BM855466 BT006706 AAP35352 DA286320 S77773 AAB34724 U69141 AAB08455 XM_006722721 XP_006722784 XM_011527899 XP_011526201 XM_011527900 XP_011526202 NM_000159 NP_000150 NM_013976 NP_039663 NR_102316 NR_102317 |
Function | Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. {ECO:0000269|PubMed:17176108, ECO:0000269|PubMed:6423663, ECO:0000269|PubMed:8541831}. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Isoform 1 and isoform 2 are expressed in fibroblasts and liver. |
Top Pathways | Lysine degradation, Fatty acid degradation, Tryptophan metabolism |
Human GCDH full length protein - ab98118 from Abcam
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GCD / GCDH Antibody Blocking Peptide - LS-E2033 from LifeSpan Bioscience
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GCD / GCDH Antibody Blocking Peptide - LS-E16024 from LifeSpan Bioscience
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GCD / GCDH Antibody Blocking Peptide - LS-E16031 from LifeSpan Bioscience
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GCD / GCDH Antibody Blocking Peptide - LS-E16030 from LifeSpan Bioscience
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GCDH Recombinant Protein - H00002639-P01 from Novus Biologicals
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Recombinant Human GCDH Protein - NBP1-50838 from Novus Biologicals
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GCDH-Antibody-C-term-Blocking-peptide - BP12905b from Abgent, a WuXi AppTec company
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GCDH Protein (OPPA02307) - OPPA02307 from Aviva Systems Biology
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Human Glutaryl-Coenzyme Dehydrogenase protein - orb90107 from Biorbyt
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Human GCDH R protein - orb163547 from Biorbyt
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GCDH Blocking Peptide - 33R-8632 from Fitzgerald
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GCDH Blocking Peptide - 33R-3897 from Fitzgerald
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GCDH protein (His tag) - 80R-1384 from Fitzgerald
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GCD / GCDH (45-438, His-tag) - AR09559PU-L from Acris Antibodies
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GCD / GCDH (45-438, His-tag) - AR09559PU-N from Acris Antibodies
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GCD / GCDH - H00002639-P01-10 from Acris Antibodies
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GCD / GCDH - H00002639-P01-25 from Acris Antibodies
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Glutaryl-Coenzyme A Dehydrogenase, Human Recombinant - 228-12559-1 from RayBiotech
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Recombinant Human Glutaryl-Coenzyme A Dehydrogenase - 228-12559-2 from RayBiotech
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Recombinant Human Glutaryl-Coenzyme A Dehydrogenase - 228-12559-3 from RayBiotech
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GCDH, 45-438aa, Human, His tag, E.coli - 01-1877 from ARP American Research Products
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GCDH, Human, Recombinant - 19-CG34 from ARP American Research Products
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GCDH fusion protein - ag6713 from Proteintech Group
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GCDH fusion protein - Ag6731 from Proteintech Group
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