GCDH

Gene Symbol GCDH
Entrez Gene 2639
Alt Symbol ACAD5, GCD
Species Human
Gene Type protein-coding
Description glutaryl-CoA dehydrogenase
Other Description glutaryl-CoA dehydrogenase, mitochondrial|glutaryl-Coenzyme A dehydrogenase
Swissprots O14719 A8K2Z2 Q92947
Accessions AAB51174 AAC52079 AER00473 EAW84324 EAW84325 EAW84326 Q92947 AK098370 AK290407 BAF83096 AK296446 BAG59097 AK298772 BAG60914 AK300841 BAG62492 AK309892 AU135567 BC002579 AAH02579 BM855466 BT006706 AAP35352 DA286320 S77773 AAB34724 U69141 AAB08455 XM_006722721 XP_006722784 XM_011527899 XP_011526201 XM_011527900 XP_011526202 NM_000159 NP_000150 NM_013976 NP_039663 NR_102316 NR_102317
Function Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. {ECO:0000269|PubMed:17176108, ECO:0000269|PubMed:6423663, ECO:0000269|PubMed:8541831}.
Subcellular Location Mitochondrion matrix.
Tissue Specificity Isoform 1 and isoform 2 are expressed in fibroblasts and liver.
Top Pathways Lysine degradation, Fatty acid degradation, Tryptophan metabolism

GCDH (C-16) - sc-167961 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GCDH (K-25) - sc-133610 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
GCDH (K-25): sc-133610. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human muscle tissue showing cytoplasmic localization.

Anti-GCDH antibody - ab75324 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCDH antibody - ab67103 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GCDH antibody (ab67103) at 1/500 dilution + human liver tissue lysate at 25 µg/mlSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-GCDH antibody - ab103415 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GCDH antibody (ab103415) at 5 µg/ml + Human kidney tissue lysate at 50 µg

Anti-GCDH antibody [3E9BA3BF5] - ab112998 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E9BA3BF5
ab112998 at 1 µg/ml staining GCDH in fibroblast cells by immunocytochemistry (4% paraformaldehyde fixed and 0.1% Triton X-100 permeabilized) followed by Alexa Fluor® 594 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1 hour (red). Nuclei were stained with DAPI.

Anti-GCDH antibody [EPR14864(B)] - ab182152 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14864(B)
Flow cytometric analysis of PC3 cells (paraformaldehyde-fixed, 2%) labeling GCDH with ab182152 at 1/80 dilution (red) or a rabbit IgG (negative) (green), followed by Goat anti rabbit IgG (FITC) secondary at 1/150 dilution.

Anti-GCDH antibody - C-terminal - ab171403 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GCDH antibody - C-terminal (ab171403) at 1/100 dilutionLane 1 : Lysate from nontransfected 293 cellsLane 2 : Lysate from 293 cells transiently transfected with GCDHLysates/proteins at 2 µg per lane.

Anti-GCD / GCDH Antibody (N-Terminus) - LS-C144873 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody - LS-C154771 from LifeSpan Bioscience

Prices $295.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa336-365, APC) - LS-C214636 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa336-365, AP) - LS-C214637 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa336-365, Biotin) - LS-C214638 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa360-409) - LS-C135134 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GCDH antibody LS-C135134 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-GCD / GCDH Antibody (aa336-365, FITC) - LS-C214639 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa336-365, Azide-free, HRP) - LS-C214640 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody - LS-C311165 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa336-365, PE) - LS-C214641 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody - LS-C307655 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GCD / GCDH Antibody (aa146-195) - LS-C80588 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-GCD / GCDH Antibody (aa335-365) - LS-C321577 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCD / GCDH Antibody (C-Terminus) - LS-C80584 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
GCDH antibody LS-C80584 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

Anti-GCD / GCDH Antibody (aa336-365) - LS-C166409 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GCDH Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

GCDH Antibody - NBP1-54737 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCDH Antibody [NBP1-54737] - HepG2 tissue lysate at a concentration of 2.5ug/ml.

GCDH Antibody - NBP2-16622 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCDH Antibody [NBP2-16622] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE gel, diluted at 1:1000.
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