Gene Symbol | E2F3 |
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Entrez Gene | 1871 |
Alt Symbol | E2F-3 |
Species | Human |
Gene Type | protein-coding |
Description | E2F transcription factor 3 |
Other Description | transcription factor E2F3 |
Swissprots | Q68DT0 O00716 Q9BZ44 Q15000 |
Accessions | AAN17846 EAW55421 EAW55422 EAW55423 O00716 BC016847 AAH16847 BC099908 AAH99908 BC114554 AAI14555 BC156367 AAI56368 BC172526 AAI72526 BU633769 CR749285 CAH18140 D38550 BAA07553 HG499031 W38841 Y10479 CAA71504 XM_005248865 XP_005248922 XM_005248866 XP_005248923 XM_011514324 XP_011512626 XM_011514325 XP_011512627 XM_011514326 XP_011512628 XM_011514327 XP_011512629 XM_011514328 XP_011512630 XM_011514329 XP_011512631 XR_926084 NM_001243076 NP_001230005 NM_001949 NP_001940 |
Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity). {ECO:0000250|UniProtKB:O35261}. |
Subcellular Location | Nucleus. |
Top Pathways | MicroRNAs in cancer, Cell cycle, HTLV-I infection, Prostate cancer, Glioma |
Human E2F3 full length protein - ab114534 from Abcam
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Human E2F3 protein fragment - ab152351 from Abcam
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Mouse E2F3 peptide - ab99875 from Abcam
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E2F3 Antibody Blocking Peptide - LS-E3420 from LifeSpan Bioscience
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E2F3 Antibody Blocking Peptide - LS-E13665 from LifeSpan Bioscience
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Recombinant Human E2F3 Protein - H00001871-P01 from Novus Biologicals
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E2F3-Antibody-Center-Blocking-Peptide - BP14598c from Abgent, a WuXi AppTec company
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E2F3 Blocking Peptide - 33R-5185 from Fitzgerald
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E2F3 - H00001871-P01-10 from Acris Antibodies
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E2F3 - H00001871-P01-25 from Acris Antibodies
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E2F3 - H00001871-Q01-10 from Acris Antibodies
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E2F3 - H00001871-Q01-25 from Acris Antibodies
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E2F3 Peptide - 7929P from ProSci
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E2F3 fusion protein - Ag14560 from Proteintech Group
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E2F3 fusion protein - ag3039 from Proteintech Group
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Recombinant Human E2F3 - E2F3-27375TH from Creative Biomart
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Recombinant Human E2F3, His-tagged - E2F3-12247H from Creative Biomart
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Recombinant E2F Transcription Factor 3 (E2F3) - RPJ183Hu01 from Uscn Life Science Inc.
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Recombinant E2F Transcription Factor 3 (E2F3) - RPJ183Hu01 from Cloud-clone
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Recombinant Human Transcription factor E2F3(E2F3) - CSB-YP007342HU CSB-EP007342HU CSB-BP007342HU CSB-MP007342HU from Cusabio
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E2F3 (full length, N-term HIS tag) - TP760363 from Acris Antibodies
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E2F3 Peptide, Human - M34GP04666H from Creative Peptides
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E2F3 Recombinant Protein Antigen - NBP2-57709PEP from Novus Biologicals
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Recombinant Human E2F3 Protein, His-tagged - E2F3-118H from Creative Biomart
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Recombinant Human E2F3 Protein, GST-tagged - E2F3-3006H from Creative Biomart
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