Gene Symbol | E2F3 |
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Entrez Gene | 1871 |
Alt Symbol | E2F-3 |
Species | Human |
Gene Type | protein-coding |
Description | E2F transcription factor 3 |
Other Description | transcription factor E2F3 |
Swissprots | Q68DT0 O00716 Q9BZ44 Q15000 |
Accessions | AAN17846 EAW55421 EAW55422 EAW55423 O00716 BC016847 AAH16847 BC099908 AAH99908 BC114554 AAI14555 BC156367 AAI56368 BC172526 AAI72526 BU633769 CR749285 CAH18140 D38550 BAA07553 HG499031 W38841 Y10479 CAA71504 XM_005248865 XP_005248922 XM_005248866 XP_005248923 XM_011514324 XP_011512626 XM_011514325 XP_011512627 XM_011514326 XP_011512628 XM_011514327 XP_011512629 XM_011514328 XP_011512630 XM_011514329 XP_011512631 XR_926084 NM_001243076 NP_001230005 NM_001949 NP_001940 |
Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity). {ECO:0000250|UniProtKB:O35261}. |
Subcellular Location | Nucleus. |
Top Pathways | MicroRNAs in cancer, Cell cycle, HTLV-I infection, Prostate cancer, Glioma |
E2F-3 (PG30) - sc-56665 from Santa Cruz Biotechnology
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E2F-3 (D-2) - sc-28308 from Santa Cruz Biotechnology
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E2F-3 (H-110) - sc-22822 from Santa Cruz Biotechnology
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E2F-3 (N-20) - sc-879 from Santa Cruz Biotechnology
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E2F-3 (PG14) - sc-69683 from Santa Cruz Biotechnology
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E2F-3 (C-18) - sc-878 from Santa Cruz Biotechnology
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E2F-3 (PG37) - sc-69684 from Santa Cruz Biotechnology
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E2F-3 (TFE36) - sc-56666 from Santa Cruz Biotechnology
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E2F-3 (0.N.263) - sc-71018 from Santa Cruz Biotechnology
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Anti-E2F3 antibody - ab74180 from Abcam
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Anti-E2F3 antibody - ab54945 from Abcam
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Anti-E2F3 antibody [3E2F04] - ab150775 from Abcam
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Anti-E2F3 antibody [PG30] - ab11843 from Abcam
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Anti-E2F3 antibody - C-terminal - ab181476 from Abcam
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Anti-E2F3 Antibody (clone 3E2F04, Azide-free) - LS-C87466 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa336-426, clone 10C30, Azide-free) - LS-C183580 from LifeSpan Bioscience
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Anti-E2F3 Antibody (clone 3E2F04) - LS-C87464 from LifeSpan Bioscience
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Anti-E2F3 Antibody (clone SPM393) - LS-C188977 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa151-180, APC) - LS-C256435 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa151-180, AP) - LS-C256436 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa151-180, Biotin) - LS-C256437 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa151-180, PE) - LS-C256442 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa151-180, FITC) - LS-C256438 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa151-180, Azide-free, HRP) - LS-C256439 from LifeSpan Bioscience
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Anti-E2F3 Antibody (aa150-180) - LS-C320996 from LifeSpan Bioscience
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