Gene Symbol | GPI |
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Entrez Gene | 2821 |
Alt Symbol | AMF, GNPI, NLK, PGI, PHI, SA-36, SA36 |
Species | Human |
Gene Type | protein-coding |
Description | glucose-6-phosphate isomerase |
Other Description | autocrine motility factor|glucose phosphate isomerase|hexose monophosphate isomerase|hexosephosphate isomerase|neuroleukin|oxoisomerase|phosphoglucose isomerase|phosphohexomutase|phosphohexose isomerase|phosphosaccharomutase|sperm antigen 36|sperm antigen-36 |
Swissprots | Q9BSK5 Q9BRD3 Q9UHE6 B4DG39 P06744 |
Accessions | AAP72966 P06744 AB209575 BAD92812 AK025421 AK129884 AK130102 AK293446 BAG56947 AK294396 BAG57650 AK301103 BAG62702 BC004982 AAH04982 BC006342 BM664761 BX641158 CR745343 DC299841 DC342043 DQ892924 ABM83850 DQ896173 ABM87172 FY213211 K03515 AAA36368 X16539 XM_005258764 XP_005258821 XM_006723148 XP_006723211 XM_011526754 XP_011525056 XM_011526755 XP_011525057 NM_000175 NP_000166 NM_001184722 NP_001171651 NM_001289789 NP_001276718 NM_001289790 NP_001276719 |
Function | Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. {ECO:0000269|PubMed:11004567, ECO:0000269|PubMed:11437381}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11437381}. Secreted {ECO:0000269|PubMed:11437381}. |
Top Pathways | Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Amino sugar and nucleotide sugar metabolism, Carbon metabolism, Starch and sucrose metabolism |
Human Glucose 6 phosphate isomerase full length protein - ab87625 from Abcam
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Human Glucose 6 phosphate isomerase full length protein - ab179980 from Abcam
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Human Glucose 6 phosphate isomerase peptide - ab85818 from Abcam
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Human Glucose 6 phosphate isomerase peptide - ab86951 from Abcam
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NLK Antibody Blocking Peptide - LS-E2819 from LifeSpan Bioscience
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NLK Antibody Blocking Peptide - LS-E9040 from LifeSpan Bioscience
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NLK Antibody Blocking Peptide - LS-E20710 from LifeSpan Bioscience
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NLK Recombinant Protein - H00051701-P01 from Novus Biologicals
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NLK Partial Recombinant Protein - H00051701-Q01 from Novus Biologicals
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Recombinant Human NLK Protein - P4735 from Novus Biologicals
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NLK Peptide - P2554 from Novus Biologicals
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PHI-rat - SP2798b from Abgent, a WuXi AppTec company
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PHI-rat - SP2798a from Abgent, a WuXi AppTec company
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GPI-Antibody-C-term-Blocking-Peptide - BP9786b from Abgent, a WuXi AppTec company
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GPI (aa81-93) blocking peptide - GTX88240-PEP from GeneTex
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GPI blocking peptide - GTX88241-PEP from GeneTex
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Recombinant human Glucose-6-phosphate isomerase (OPCA00327) - OPCA00327 from Aviva Systems Biology
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Human GPI protein - orb245027 from Biorbyt
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GPI protein (His tag) - 80R-1169 from Fitzgerald
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GPI protein (His tag) - 80R-3414 from Fitzgerald
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NLK Blocking Peptide - 33R-8051 from Fitzgerald
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Human GPI Protein - abx066794 from Abbexa
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Glucose 6 Phosphate Isomerase Peptide - AC21-2049-P from Abcore
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Glucose 6 Phosphate Isomerase Peptide - AC21-2050-P from Abcore
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Glucose-6-phosphate isomerase (GPI) (1-558, His-tag) - AR09229PU-L from Acris Antibodies
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