Gene Symbol | PMM1 |
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Entrez Gene | 5372 |
Alt Symbol | Sec53 |
Species | Human |
Gene Type | protein-coding |
Description | phosphomannomutase 1 |
Other Description | PMM 1|PMMH-22|brain glucose-1,6-bisphosphatase |
Swissprots | A8K003 Q92871 Q92586 |
Accessions | EAW60443 EAW60444 Q92871 AK094811 AK130449 AK289368 BAF82057 AK316580 BAG38168 BC010855 AAH10855 BC016818 AAH16818 CR456544 CAG30430 CU013144 CAK54575 CU013432 CAK54874 D87810 BAA13460 U62526 AAC51117 U86070 AAC00023 XM_005261638 XP_005261695 XM_005261641 XP_005261698 XM_005261642 XP_005261699 XM_011530229 XP_011528531 XM_011530230 XP_011528532 XM_011530231 XP_011528533 XM_011530232 XP_011528534 NM_002676 NP_002667 |
Function | Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. {ECO:0000269|PubMed:16540464}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Strong expression in liver, heart, brain, and pancreas; lower expression in skeletal muscle. |
Top Pathways | Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism |
PMM1 (E-6) - sc-393095 from Santa Cruz Biotechnology
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PMM1 (D-19) - sc-86201 from Santa Cruz Biotechnology
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PMM1 (C-19) - sc-86200 from Santa Cruz Biotechnology
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Anti-PMM1 antibody - ab94606 from Abcam
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Anti-PMM1 antibody - ab201192 from Abcam
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Anti-PMM1 antibody [EPR17844] - ab202058 from Abcam
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Anti-PMM1 antibody [EPR17844-44] - ab202059 from Abcam
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Anti-PMM1 Antibody (N-Terminus) - LS-C111910 from LifeSpan Bioscience
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PMM1/Phosphomannomutase 1 Antibody - NBP1-87055 from Novus Biologicals
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PMM1/Phosphomannomutase 1 Antibody - NBP1-55475 from Novus Biologicals
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Anti-PMM1 antibody produced in rabbit - HPA030712 from Sigma-Aldrich
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Anti-PMM1, (N-terminal) antibody produced in rabbit - SAB2104512 from Sigma-Aldrich
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Anti-PMM1 (218-230) antibody produced in rabbit - SAB1100326 from Sigma-Aldrich
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PMM1 antibody - N-terminal region (ARP56401_P050) - ARP56401_P050 from Aviva Systems Biology
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PMM1 antibody - 70R-19367 from Fitzgerald
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PMM1 antibody - 70R-3894 from Fitzgerald
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Phosphomannomutase 1 Antibody - abx114494 from Abbexa
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PMM1 antibody - 11252-2-AP from Acris Antibodies
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Anti-PMM1 Antibody - AC17-0037 from Abcore
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Anti-PMM1 Antibody (AMCA) - AC17-0037-01 from Abcore
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Anti-PMM1 Antibody (AP) - AC17-0037-02 from Abcore
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Anti-PMM1 Antibody (APC) - AC17-0037-03 from Abcore
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Anti-PMM1 Antibody (APC-Cy5.5) - AC17-0037-04 from Abcore
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Anti-PMM1 Antibody (APC-Cy7) - AC17-0037-05 from Abcore
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Anti-PMM1 Antibody (Avidin) - AC17-0037-06 from Abcore
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