| Gene Symbol |
SCD
|
| Entrez Gene |
6319
|
| Alt Symbol |
FADS5, MSTP008, SCD1, SCDOS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
stearoyl-CoA desaturase (delta-9-desaturase)
|
| Other Description |
acyl-CoA desaturase|delta(9)-desaturase|delta-9 desaturase|delta-9-desaturase|fatty acid desaturase|predicted protein of HQ0998|stearoyl-CoA desaturase opposite strand
|
| Swissprots |
Q16150 D3DR68 Q5W037 O00767 Q5W038 Q96KF6 Q6GSS4 Q9BS07 Q9Y695 B2R5U0 Q53GR9
|
| Accessions |
AAK54510 EAW49827 EAW49828 EAW49829 EAW49830 O00767 AB032261 BAA93510 AB208982 BAD92219 AF097514 AAD29870 AF109362 AAQ13510 AI740935 AK222862 BAD96582 AK312312 BAG35237 BC005807 AAH05807 BC062303 AAH62303 BI827092 BM546583 BU940035 CD245516 CF454075 S70284 AAB30631 Y13647 CAA73998 NM_005063 NP_005054
|
| Function |
Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
PPAR signaling pathway, AMPK signaling pathway, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism
|
![Western Blot: SCD Overexpression Lysate (Adult Normal) [NBL1-15724] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SCD.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9585_SCD%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15724-img0002.jpg)