HPN

Gene Symbol	HPN
Entrez Gene	3249
Alt Symbol	TMPRSS1
Species	Human
Gene Type	protein-coding
Description	hepsin
Other Description	serine protease hepsin|transmembrane protease serine 1
Swissprots	B2RDS4 P05981
Accessions	CAC60387 CCQ43929 P05981 AK091988 AK095160 AK293622 BAH11550 AK315655 BAG38021 BC025716 AAH25716 DQ892119 ABM83045 DQ895314 ABM86240 EU644753 ACD02430 M18930 AAA36013 X07002 CAA30058 X07732 CAA30558 XM_005258838 XP_005258895 XM_006723181 XP_006723244 XM_011526891 XP_011525193 NM_002151 NP_002142 NM_182983 NP_892028
Function	Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2. {ECO:0000269|PubMed:15839837, ECO:0000269|PubMed:21875933, ECO:0000269|PubMed:24227843}.
Subcellular Location	Membrane; Single-pass type II membrane protein.
Tissue Specificity	Present in most tissues, with the highest level in liver.
Top Pathways	Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Hepsin peptide - ab45257 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Hepsin peptide - ab45258 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Hepsin peptide - ab45259 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Hepsin peptide - ab45260 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Hepsin full length protein - ab114907 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Hepsin Protein - H00003249-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Hepsin, CF - 4776-SE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Arg45-Leu417 (Asp161Glu & Arg162Lys), with a C-terminal 10-His tag

Recombinant Human Hepsin GMP, CF - 4776-GMP-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Arg45-Leu417 (Asp161Glu & Arg162Lys), with a C-terminal 10-His tag

Recombinant Human Hepsin GMP, CF - 4776-GMP-01M from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Arg45-Leu417 (Asp161Glu & Arg162Lys), with a C-terminal 10-His tag

Serine protease hepsin (HPN) - H00003249-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Serine protease hepsin (HPN) - H00003249-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HPN fusion protein - ag15103 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant Human HPN - HPN-26788TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Serine protease hepsin(HPN) - CSB-YP010704HU CSB-EP010704HU CSB-BP010704HU CSB-MP010704HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Hepsin GMP Protein, CF - 4776-GMP from R&D Systems Category Protein Prices $365.00, $7,600.00 Sizes 10 µg, 1 mg Source Mouse myeloma cell line, NS0-derived Arg45-Leu417 (Asp161Glu & Arg162Lys), with a C-terminal 10-His tag Manufactured and tested under cGMP guidelines. Species Human

Recombinant Human Hepsin Protein, CF - 4776-SE from R&D Systems Category Protein Prices $329.00 Sizes 10 µg Source Mouse myeloma cell line, NS0-derived Arg45-Leu417 (Asp161Glu & Arg162Lys), with a C-terminal 10-His tag Species Human

HPN Protein - abx163770 from Abbexa Category Protein Species Human

Hepsin Recombinant Protein Antigen - NBP1-86931PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HPN-Antibody-Center-Blocking-Peptide - BP9511c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HPN-Blocking-Peptide-Center - BP21383c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HPN Peptide, Human - M34GP07230H from Creative Peptides Category Peptide Source Synthetic. Species Human

Serine protease hepsin (191-199) - ta-347 from Creative Peptides Category Peptide Source Homo sapiens (human)

Serine protease hepsin (229-237) - ta-348 from Creative Peptides Category Peptide Source Homo sapiens (human)

Serine protease hepsin (268-276) - ta-349 from Creative Peptides Category Peptide Source Homo sapiens (human)

Recombinant Mouse Hepsin Protein, CF - 9156-SE from R&D Systems Category Protein Prices $339.00 Sizes 10 µg Source Mouse myeloma cell line, NS0-derived Gln44-Pro416 (Asp160Glu & Arg161Lys), with a C-terminal 10-His tag Species Mouse

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