HPN

Gene Symbol	HPN
Entrez Gene	3249
Alt Symbol	TMPRSS1
Species	Human
Gene Type	protein-coding
Description	hepsin
Other Description	serine protease hepsin|transmembrane protease serine 1
Swissprots	B2RDS4 P05981
Accessions	CAC60387 CCQ43929 P05981 AK091988 AK095160 AK293622 BAH11550 AK315655 BAG38021 BC025716 AAH25716 DQ892119 ABM83045 DQ895314 ABM86240 EU644753 ACD02430 M18930 AAA36013 X07002 CAA30058 X07732 CAA30558 XM_005258838 XP_005258895 XM_006723181 XP_006723244 XM_011526891 XP_011525193 NM_002151 NP_002142 NM_182983 NP_892028
Function	Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2. {ECO:0000269|PubMed:15839837, ECO:0000269|PubMed:21875933, ECO:0000269|PubMed:24227843}.
Subcellular Location	Membrane; Single-pass type II membrane protein.
Tissue Specificity	Present in most tissues, with the highest level in liver.
Top Pathways	Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-HPN-cDNA-Clone - DC05509 from Abgent, a WuXi AppTec company Prices $562.95 Sizes 10 µg Species Human Accession BC025716

HPN - MBS1271896 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC025716

Human HPN ORF Clone(NM_002151.2) - CDCL166438 from Creative Biomart Species Human Accession NM_002151.2

Human Hepsin transcript variant 1 Gene ORF cDNA clone in cloning vector - HG11177-M from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11177-CF from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11177-NH from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11177-CM from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11177-CH from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11177-CY from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11177-ACR from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid - HG11177-UT from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11177-ACG from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11177-M-F from Sino Biological Species Human

Human HPN transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11177-M-N from Sino Biological Species Human Accession NM_182983.1

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11177-NF from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11177-NM from Sino Biological Species Human

Human Hepsin transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11177-NY from Sino Biological Species Human

Mouse Hepsin (NP_032307) VersaClone cDNA - RDC1327 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human Hepsin (NP_002142) VersaClone cDNA - RDC1328 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human HPN ORF Clone (BC025716) - CDCS410648 from Creative biogene Species Human Accession P05981

Human HPN gene - orb91670 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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