Gene Symbol | CALY |
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Entrez Gene | 50632 |
Alt Symbol | DRD1IP, NSG3 |
Species | Human |
Gene Type | protein-coding |
Description | calcyon neuron-specific vesicular protein |
Other Description | D1 dopamine receptor-interacting protein|calcyon D1 dopamine receptor-interacting protein (CALCYON)|calcyon protein|dopamine receptor D1 interacting protein|neuron-specific vesicular protein calcyon |
Swissprots | Q5VWX3 Q5VWY6 Q9NYX4 Q5VWY5 |
Accessions | EAW61334 EAW61335 Q9NYX4 AF225903 AAF34714 BC038978 AAH38978 BI914942 BP392207 HG503392 XM_005252685 XP_005252742 XM_011539835 XP_011538137 XM_011539836 XP_011538138 XM_011539837 XP_011538139 XM_011539838 XP_011538140 XM_011539839 XP_011538141 NM_015722 NP_056537 |
Function | Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. {ECO:0000269|PubMed:16595675}. |
Subcellular Location | Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. |
Tissue Specificity | Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non- schizophrenics. {ECO:0000269|PubMed:12622665}. |
Top Pathways | Dopaminergic synapse |
Calcyon (E-20) - sc-10837 from Santa Cruz Biotechnology
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Calcyon (G-8) - sc-271004 from Santa Cruz Biotechnology
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Calcyon (N-17) - sc-10836 from Santa Cruz Biotechnology
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Calcyon (H-175) - sc-50400 from Santa Cruz Biotechnology
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Anti-Calcyon antibody - ab191993 from Abcam
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Anti-CALY Antibody - LS-C342119 from LifeSpan Bioscience
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Anti-CALY Antibody (aa141-190) - LS-C135003 from LifeSpan Bioscience
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Anti-CALY Antibody (aa125-175) - LS-C291086 from LifeSpan Bioscience
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CALY Antibody - NBP1-91225 from Novus Biologicals
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Calcyon/Drd1ip Polyclonal Antibody - bs-11719R from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11719R-A350 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11719R-A488 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11719R-A555 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11719R-A647 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, Cy3 Conjugated - bs-11719R-Cy3 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, Cy5 Conjugated - bs-11719R-Cy5 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, Cy5.5 Conjugated - bs-11719R-Cy5.5 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, Cy7 Conjugated - bs-11719R-Cy7 from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, FITC Conjugated - bs-11719R-FITC from Bioss
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Rabbit Anti-Calcyon/Drd1ip Polyclonal Antibody, PE Conjugated - bs-11719R-PE from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, Biotin Conjugated - bs-11719R-Biotin from Bioss
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Calcyon/Drd1ip Polyclonal Antibody, HRP Conjugated - bs-11719R-HRP from Bioss
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Anti-CALY antibody produced in rabbit - HPA042283 from Sigma-Aldrich
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Anti-DRD1IP (161-174) antibody produced in rabbit - D7694 from Sigma-Aldrich
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CALY-Antibody-N-term - AP21268a from Abgent, a WuXi AppTec company
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