Gene Symbol | NID2 |
---|---|
Entrez Gene | 22795 |
Alt Symbol | NID-2 |
Species | Human |
Gene Type | protein-coding |
Description | nidogen 2 (osteonidogen) |
Other Description | nidogen-2|osteonidogen |
Swissprots | Q14112 O43710 A8K6I7 B4DU19 |
Accessions | BAA24112 CCQ43398 EAW65658 Q14112 AJ223500 CAA11418 AK291652 BAF84341 AK298542 BAG60740 AK300462 BAG62181 AL701794 AU119925 BC035608 AAH35608 BM719690 BX648241 CAI56714 CA413165 D86425 BAA13087 XM_005267405 XP_005267462 XM_005267406 XP_005267463 XM_005267407 XP_005267464 NM_007361 NP_031387 |
Function | Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. |
Tissue Specificity | Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle. |