Gene Symbol |
NID2
|
Entrez Gene |
22795
|
Alt Symbol |
NID-2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nidogen 2 (osteonidogen)
|
Other Description |
nidogen-2|osteonidogen
|
Swissprots |
Q14112 O43710 A8K6I7 B4DU19
|
Accessions |
BAA24112 CCQ43398 EAW65658 Q14112 AJ223500 CAA11418 AK291652 BAF84341 AK298542 BAG60740 AK300462 BAG62181 AL701794 AU119925 BC035608 AAH35608 BM719690 BX648241 CAI56714 CA413165 D86425 BAA13087 XM_005267405 XP_005267462 XM_005267406 XP_005267463 XM_005267407 XP_005267464 NM_007361 NP_031387
|
Function |
Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane.
|
Tissue Specificity |
Heart, placenta and bone. Less in pancreas, kidney and skeletal muscle.
|