| Gene Symbol |
NKD1
|
| Entrez Gene |
85407
|
| Alt Symbol |
Naked1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
naked cuticle homolog 1 (Drosophila)
|
| Other Description |
Dvl-binding protein|naked cuticle-1|naked-1|protein naked cuticle homolog 1
|
| Swissprots |
B2RC39 Q969G9 Q8WZ08
|
| Accessions |
EAW82761 Q969G9 AB062886 BAB70500 AF289584 AAL55768 AF358135 AAK57484 AK000276 AK021701 AK023784 AK314930 BAG37436 AY061883 AAL32374 BC051288 AAH51288 HG508049 XM_011523399 XP_011521701 XM_011523400 XP_011521702 XM_011523401 XP_011521703 NM_033119 NP_149110
|
| Function |
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. {ECO:0000269|PubMed:11752446, ECO:0000269|PubMed:15687260, ECO:0000269|PubMed:16567647}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}. Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen. {ECO:0000269|PubMed:11604995}.
|
| Top Pathways |
Wnt signaling pathway, Hippo signaling pathway
|